[HTML][HTML] MicroRNA-based therapy for glioblastoma: Opportunities and challenges
Q Lei, Y Yang, W Zhou, W Liu, Y Li, N Qi, Q Li… - European Journal of …, 2023 - Elsevier
Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor and
is characterized by high mortality and morbidity rates and unpredictable clinical behavior …
is characterized by high mortality and morbidity rates and unpredictable clinical behavior …
Exosomes and micro-RNAs in aging process
Y Hamdan, L Mazini, G Malka - Biomedicines, 2021 - mdpi.com
Exosomes are the main actors of intercellular communications and have gained great
interest in the new cell-free regenerative medicine. These nanoparticles are secreted by …
interest in the new cell-free regenerative medicine. These nanoparticles are secreted by …
MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer
R Dinami, L Pompili, E Petti, M Porru… - EMBO Molecular …, 2023 - embopress.org
The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key
role in the maintenance of telomere structure and function. It is highly expressed in different …
role in the maintenance of telomere structure and function. It is highly expressed in different …
Combining single-cell RNA sequencing of peripheral blood mononuclear cells and exosomal transcriptome to reveal the cellular and genetic profiles in COPD
Y Pei, Y Wei, B Peng, M Wang, W Xu, Z Chen, X Ke… - Respiratory …, 2022 - Springer
Background It has been a long-held consensus that immune reactions primarily mediate the
pathology of chronic obstructive pulmonary disease (COPD), and that exosomes may …
pathology of chronic obstructive pulmonary disease (COPD), and that exosomes may …
A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models
N Sadeghipour, SU Kumar, TF Massoud… - Scientific Reports, 2022 - nature.com
Glioblastoma (GBM) is the most common malignant brain tumor. Available treatments have
limited success because most patients develop chemoresistance. Alternative strategies are …
limited success because most patients develop chemoresistance. Alternative strategies are …
Exploring the role of microRNAs in glioma progression, prognosis, and therapeutic strategies
O Tluli, M Al-Maadhadi, AA Al-Khulaifi, AF Akomolafe… - Cancers, 2023 - mdpi.com
Simple Summary Despite advancements in healthcare and research, the occurrence of
gliomas, a type of brain tumor, continues to rise. Emerging evidence has proven that …
gliomas, a type of brain tumor, continues to rise. Emerging evidence has proven that …
Circulating liquid biopsy biomarkers in glioblastoma: Advances and challenges
AA Seyhan - International Journal of Molecular Sciences, 2024 - pmc.ncbi.nlm.nih.gov
Gliomas, particularly glioblastoma (GBM), represent the most prevalent and aggressive
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …
[HTML][HTML] Advancements in Telomerase-Targeted Therapies for Glioblastoma: A Systematic Review
G Pennisi, P Bruzzaniti, B Burattini… - International Journal of …, 2024 - mdpi.com
Glioblastoma (GBM) is a primary CNS tumor that is highly lethal in adults and has limited
treatment options. Despite advancements in understanding the GBM biology, the standard …
treatment options. Despite advancements in understanding the GBM biology, the standard …
MicroRNAs regulating SOX2 in cancer progression and therapy response
The proliferation, metastasis and therapy response of tumour cells are tightly regulated by
interaction among various signalling networks. The microRNAs (miRNAs) can bind to 3 …
interaction among various signalling networks. The microRNAs (miRNAs) can bind to 3 …
New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs
Background Glioblastoma (GBM) is the most frequent type of primary brain cancer, having a
median survival of only 15 months. The current standard of care includes a combination of …
median survival of only 15 months. The current standard of care includes a combination of …