Mechanisms Underlying Proton Release in CLC-type F–/H+ Antiporters
The CLC family of anion channels and transporters includes Cl–/H+ exchangers (blocked by
F–) and F–/H+ exchangers (or CLCFs). CLCFs contain a glutamate (E318) in the central …
F–) and F–/H+ exchangers (or CLCFs). CLCFs contain a glutamate (E318) in the central …
Uncovering the Mechanism of the Proton-Coupled Fluoride Transport in the CLCF Antiporter
KR Mills, H Torabifard - Journal of Chemical Information and …, 2023 - ACS Publications
Fluoride is a natural antibiotic abundantly present in the environment and, in micromolar
concentrations, is able to inhibit enzymes necessary for bacteria to survive. However, as is …
concentrations, is able to inhibit enzymes necessary for bacteria to survive. However, as is …
Fluoride Ion Binding and Translocation in the CLCF Fluoride/Proton Antiporter: Molecular Insights from Combined Quantum-Mechanical/Molecular-Mechanical …
CLCF fluoride/proton antiporters move fluoride ions out of bacterial cells, leading to fluoride
resistance in these bacteria. However, many details about their operating mechanisms …
resistance in these bacteria. However, many details about their operating mechanisms …
Anion Pathways in the NarK Nitrate/Nitrite Exchanger
NarK nitrate/nitrite antiporter imports nitrate (a mineral form of the essential element
nitrogen) into the cell and exports nitrite (a metabolite that can be toxic in high …
nitrogen) into the cell and exports nitrite (a metabolite that can be toxic in high …
Fluoride transport and inhibition across CLC transporters
Abstract The Chloride Channel (CLC) family includes proton-coupled chloride and fluoride
transporters. Despite their similar protein architecture, the former exchange two chloride ions …
transporters. Despite their similar protein architecture, the former exchange two chloride ions …
Computational approaches to investigate fluoride binding, selectivity and transport across the membrane
KR Mills, H Torabifard - Fluorine Metabolism, Transport and …, 2024 - books.google.com
Computational approaches to investigate fluoride binding, selectivity and transport across the
membrane Page 132 CHAPTER SIX Computational approaches to investigate fluoride …
membrane Page 132 CHAPTER SIX Computational approaches to investigate fluoride …