Cardiovascular diseases (CVDs), including atherosclerosis, myocardial infarction and heart
failure, are the leading causes of morbidity and mortality worldwide. Emerging evidence …

Granzymes (granule-secreted enzymes) are a family of serine proteases that have been
viewed as redundant cytotoxic enzymes since their discovery more than 30 years ago …

Stroke is a major threat to life and health in modern society, especially in the aging
population. Stroke may cause sudden death or severe sequela‐like hemiplegia. Although …

Flow cytometry is a widely used technique for immune cell analysis, offering insights into cell
composition and function. Spectral flow cytometry allows for high-dimensional analysis of …

Atherosclerotic plaques are defined by the accumulation of lipids and immune cells beneath
the endothelium of the arterial intima. CD8 T cells are among the most abundant immune …

Clonal expansion of CD8+ T cells in aged mice linked to pro-atherogenic phenotype | Nature
Reviews Cardiology Skip to main content Thank you for visiting nature.com. You are using a …