It is widely accepted that the brain and the immune system continuously interact during
normal as well as pathological functioning. Human aging is commonly accompanied by low …

Increasing attention has been given to understanding resilience to brain diseases, often
described as brain or cognitive reserve. Among the protective factors for the development of …

A consequence of normal aging is a greater susceptibility to memory impairments following
an immune challenge such as infection, surgery, or traumatic brain injury. The …

Hippocampus is one of the most vulnerable brain regions in terms of age-related
pathological change. Exercise is presumed to delay the aging process and promote health …

The P7C3 class of aminopropyl carbazole chemicals fosters the survival of neurons in a
variety of rodent models of neurodegeneration or nerve cell injury. To uncover its …

Brain-derived neurotrophic factor (BDNF) has a neurotrophic support on neuron of central
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …

An in vivo screen was performed in search of chemicals capable of enhancing neuron
formation in the hippocampus of adult mice. Eight of 1000 small molecules tested enhanced …

The mechanisms by which physical exercise benefits brain functions are not fully
understood. Here, we show that vertically oscillating head motions mimicking mechanical …

Background Muscle regeneration depends on satellite cells, myogenic stem cells that reside
on the myofiber surface. Reduced numbers and/or decreased myogenic aptitude of these …

Although chemotherapy increases the survival rate of patients with various cancers, such
treatment can induce acute or long-term cognitive dysfunction a phenomenon known as post …