Next-generation sequencing: insights to advance clinical investigations of the microbiome
CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
Applications of machine learning in human microbiome studies: a review on feature selection, biomarker identification, disease prediction and treatment
LJ Marcos-Zambrano… - Frontiers in …, 2021 - frontiersin.org
The number of microbiome-related studies has notably increased the availability of data on
human microbiome composition and function. These studies provide the essential material …
human microbiome composition and function. These studies provide the essential material …
MicrobiomeAnalyst 2.0: comprehensive statistical, functional and integrative analysis of microbiome data
Microbiome studies have become routine in biomedical, agricultural and environmental
sciences with diverse aims, including diversity profiling, functional characterization, and …
sciences with diverse aims, including diversity profiling, functional characterization, and …
Microbiome definition re-visited: old concepts and new challenges
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in …
become a topic of great scientific and public interest. As a result of this rapid growth in …
Comparison between 16S rRNA and shotgun sequencing data for the taxonomic characterization of the gut microbiota
In this paper we compared taxonomic results obtained by metataxonomics (16S rRNA gene
sequencing) and metagenomics (whole shotgun metagenomic sequencing) to investigate …
sequencing) and metagenomics (whole shotgun metagenomic sequencing) to investigate …
[HTML][HTML] Developmental trajectory of the healthy human gut microbiota during the first 5 years of life
J Roswall, LM Olsson, P Kovatcheva-Datchary… - Cell host & …, 2021 - cell.com
The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated …
established at birth. However, the succession by which different bacteria are incorporated …
Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data
MicrobiomeAnalyst is an easy-to-use, web-based platform for comprehensive analysis of
common data outputs generated from current microbiome studies. It enables researchers …
common data outputs generated from current microbiome studies. It enables researchers …
Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …
challenging and hampers insights into the structure and function of microbial communities …
Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis
The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a …
decades. However, high-throughput sequencing of the full gene has only recently become a …
Unambiguous identification of fungi: where do we stand and how accurate and precise is fungal DNA barcoding?
True fungi (Fungi) and fungus-like organisms (eg Mycetozoa, Oomycota) constitute the
second largest group of organisms based on global richness estimates, with around 3 …
second largest group of organisms based on global richness estimates, with around 3 …