Extracellular vesicles as delivery vehicles of specific cellular cargo

B Mir, C Goettsch - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) mediate cell-to-cell communication via the transfer of
biomolecules locally and systemically between organs. It has been elucidated that the …

Mechanism of cargo sorting into small extracellular vesicles

Y Chen, Y Zhao, Y Yin, X Jia, L Mao - Bioengineered, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are special membranous structures released by almost every
cell type that carry and protect some biomolecules from being degraded. They transport …

Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection

N He, S Thippabhotla, C Zhong, Z Greenberg… - Communications …, 2022 - nature.com
Extracellular vesicles (EVs), particularly nano-sized small EV exosomes, are emerging
biomarker sources. However, due to heterogeneous populations secreted from diverse cell …

hsa-miR-320a mediated exosome release under PD stress conditions rescue mitochondrial ROS and cell death in the recipient neuronal and glial cells

S Shukla, F Currim, J Singh, S Goyani… - … International Journal of …, 2023 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
dopaminergic neuronal cell death. Emerging evidence suggest exosomes as a crucial …

Lectins as potential tools for cancer biomarker discovery from extracellular vesicles

MK Islam, M Khan, K Gidwani, KW Witwer… - Biomarker …, 2023 - Springer
Extracellular vesicles (EVs) have considerable potential as diagnostic, prognostic, and
therapeutic agents, in large part because molecular patterns on the EV surface betray the …

Extracellular vesicles as novel drug-delivery systems through intracellular communications

Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Since it has been reported that extracellular vesicles (EVs) carry cargo using cell-to-cell
comminication according to various in vivo situations, they are exprected to be applied as …

[HTML][HTML] Glycometabolic regulation of the biogenesis of small extracellular vesicles

Y Harada, K Nakajima, T Suzuki, T Fukushige, K Kondo… - Cell Reports, 2020 - cell.com
The biogenesis of small extracellular vesicles (sEVs) is regulated by multiple molecular
machineries generating considerably heterogeneous vesicle populations, including …

Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells

ALE Carli, S Afshar‐Sterle, A Rai, H Fang… - …, 2021 - Wiley Online Library
Abstract Doublecortin‐like kinase 1 (DCLK1) is a putative cancer stem cell marker, a
promising diagnostic and prognostic maker for malignant tumors and a proposed driver …

Do different exosome biogenesis pathways and selective cargo enrichment contribute to exosomal heterogeneity?

S Shukla, F Currim, R Singh - Biology of the Cell, 2023 - Wiley Online Library
Exosomes are emerging intercellular communicators essential for cellular homeostasis
during development and differentiation. The dysregulation in exosome‐mediated …

Cancer nanomedicine special issue review anticancer drug delivery with nanoparticles: Extracellular vesicles or synthetic nanobeads as therapeutic tools for …

MR Zocchi, F Tosetti, R Benelli, A Poggi - Cancers, 2020 - mdpi.com
Both natural and synthetic nanoparticles have been proposed as drug carriers in cancer
treatment, since they can increase drug accumulation in target tissues, optimizing the …