The hypoxic testicle: physiology and pathophysiology

JG Reyes, JG Farias… - Oxidative Medicine …, 2012 - Wiley Online Library
Mammalian spermatogenesis is a complex biological process occurring in the seminiferous
tubules in the testis. This process represents a delicate balance between cell proliferation …

The role of oxidative stress modulators in breast cancer

H Gurer-Orhan, E Ince, D Konyar… - Current medicinal …, 2018 - ingentaconnect.com
Background: Latest data from International Agency for Cancer Research shows that breast
cancer is the leading cancer site in women and is the leading cause of death among female …

Cellular and molecular mechanisms in the hypoxic tissue: role of HIF‐1 and ROS

AB Zepeda, A Pessoa Jr, RL Castillo… - Cell biochemistry …, 2013 - Wiley Online Library
Reactive oxygen species such as superoxide anion radicals (O2−) and hydrogen peroxide
(H2O2) have for long time been recognized as undesirable by‐products of the oxidative …

Melatonin and metabolic regulation: a review

M Navarro-Alarcón, FJ Ruiz-Ojeda… - Food & function, 2014 - pubs.rsc.org
Human life expectancy has increased over the past 50 years due to scientific and medical
advances and higher food availability. However, overweight and obesity affect more than …

Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress

JG Farias, EA Herrera, C Carrasco-Pozo… - Pharmacology & …, 2016 - Elsevier
Hypoxia is the failure of oxygenation at the tissue level, where the reduced oxygen delivered
is not enough to satisfy tissue demands. Metabolic depression is the physiological …

Real-time fast scan cyclic voltammetry detection and quantification of exogenously administered melatonin in mice brain

E Castagnola, EM Robbins, KM Woeppel… - … in bioengineering and …, 2020 - frontiersin.org
Melatonin (MT) has been recently considered an excellent candidate for the treatment of
sleep disorders, neural injuries, and neurological diseases. To better investigate the actions …

[HTML][HTML] Acclimatization to chronic intermittent hypoxia in mine workers: a challenge to mountain medicine in Chile

JG Farías, D Jimenez, J Osorio, AB Zepeda… - Biological …, 2013 - SciELO Chile
In the past two decades, Chile has developed intense mining activity in the Andes mountain
range, whose altitude is over 4,000 meters above sea level. It is estimated that a workforce …

Effects of prenatal 900 MHz electromagnetic field exposures on the histology of rat kidney

M Ulubay, A Yahyazadeh, ÖG Deniz… - … journal of radiation …, 2015 - Taylor & Francis
Purpose: To research the harmful effects of prenatal exposure of 900 megahertz (MHz)
electromagnetic field (EMF) on kidneys of four-week-old male rats and to determine …

Intermittent hypoxia contributes to the lung damage by increased oxidative stress, inflammation, and disbalance in protease/antiprotease system

I Tuleta, F Stöckigt, UR Juergens, C Pizarro… - Lung, 2016 - Springer
Introduction Intermittent hypoxia as a surrogate of obstructive sleep apnea is associated with
different cardiovascular complications. However, the effects of intermittent hypoxia on the …

Influence of oxidative, carbonyl, and nitrosative stresses on the course of chronic kidney disease (analytical review)

LD Denova, DD Ivanov - Kidneys, 2022 - kidneys.zaslavsky.com.ua
Oxidative stress is a phenomenon caused by an imbalance of peroxide homeostasis. The
concept of oxidative stress was introduced in 1985 and has a clear connection with redox …