Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer
W He, Q Li, X Li - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Acetyl-CoA, as an important molecule, not only participates in multiple intracellular
metabolic reactions, but also affects the post-translational modification of proteins, playing a …
metabolic reactions, but also affects the post-translational modification of proteins, playing a …
Mitochondrial dysfunction-targeted nanosystems for precise tumor therapeutics
Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …
[HTML][HTML] Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment
Z Zhang, Y Ji, N Hu, Q Yu, X Zhang, J Li, F Wu… - Asian Journal of …, 2022 - Elsevier
Ferroptosis is a novel form of programmed cell death impelled by iron-dependent lipid
peroxidation, which may be a potential strategy for cancer therapy. Here we demonstrated …
peroxidation, which may be a potential strategy for cancer therapy. Here we demonstrated …
The interplay of oncogenic signaling, oxidative stress and ferroptosis in cancer
W Zeng, X Long, PS Liu, X Xie - International Journal of Cancer, 2023 - Wiley Online Library
Oncogene‐induced hyper‐proliferation in cancer cells is accompanied by the onset of
different stresses, including DNA‐replication stress, metabolic stress and oxidative stress …
different stresses, including DNA‐replication stress, metabolic stress and oxidative stress …
Hydrogen sulfide, an endogenous stimulator of mitochondrial function in cancer cells
C Szabo - Cells, 2021 - mdpi.com
Hydrogen sulfide (H2S) has a long history as toxic gas and environmental hazard; inhibition
of cytochrome c oxidase (mitochondrial Complex IV) is viewed as a primary mode of its …
of cytochrome c oxidase (mitochondrial Complex IV) is viewed as a primary mode of its …
Organelle‐specific mechanisms in crosstalk between apoptosis and ferroptosis
P Wu, X Zhang, D Duan, L Zhao - Oxidative Medicine and …, 2023 - Wiley Online Library
Apoptosis has been extensively studied, whereas ferroptosis is a newly discovered form of
regulated cell death that involves iron‐dependent accumulations of lipid hydroperoxides …
regulated cell death that involves iron‐dependent accumulations of lipid hydroperoxides …
Therapeutic potential of Scutellaria baicalensis Georgi in lung cancer therapy
L Xiang, Y Gao, S Chen, J Sun, J Wu, X Meng - Phytomedicine, 2022 - Elsevier
Background Globally, lung cancer is the leading cause of cancer associated mortalities. The
current conventional chemotherapy remains the preferred treatment option for lung cancer …
current conventional chemotherapy remains the preferred treatment option for lung cancer …
Metabolic health, mitochondrial fitness, physical activity, and cancer
VJ Clemente-Suárez, A Martín-Rodríguez… - Cancers, 2023 - mdpi.com
Simple Summary Recent research suggests a strong link between the functioning of
mitochondria and the development of cancer. Healthy mitochondria play a vital role in …
mitochondria and the development of cancer. Healthy mitochondria play a vital role in …
Mitochondria at work: new insights into regulation and dysregulation of cellular energy supply and metabolism
V Schirrmacher - Biomedicines, 2020 - mdpi.com
Mitochondria are of great relevance to health, and their dysregulation is associated with
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …
The hexokinase “HKDC1” interaction with the mitochondria is essential for liver cancer progression
Liver cancer (LC) is the fourth leading cause of death from cancer malignancies. Recently, a
putative fifth hexokinase, hexokinase domain containing 1 (HKDC1), was shown to have …
putative fifth hexokinase, hexokinase domain containing 1 (HKDC1), was shown to have …