Impact of glucose-lowering medications on cardiovascular and metabolic risk in type 2 diabetes
Type 2 Diabetes Mellitus (T2DM) is associated with a high risk of atherosclerotic
cardiovascular (CV) disease. Among the well-known pathophysiologic factors, crucial roles …
cardiovascular (CV) disease. Among the well-known pathophysiologic factors, crucial roles …
Epidemiology and economic burden of cardiovascular disease in patients with type 2 diabetes mellitus in Spain: a systematic review
E Artime, I Romera, S Díaz-Cerezo, E Delgado - Diabetes Therapy, 2021 - Springer
Introduction Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in
people with type 2 diabetes mellitus (T2DM). The objectives of this systematic literature …
people with type 2 diabetes mellitus (T2DM). The objectives of this systematic literature …
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
M Zhao, S Wang, A Zuo, J Zhang, W Wen… - Cellular & Molecular …, 2021 - Springer
Background Endothelial cell (EC) injury accelerates the progression of diabetic
macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible …
macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible …
Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro
G Gao, L Fu, Y Xu, L Tao, T Guo, G Fang… - Frontiers in …, 2022 - frontiersin.org
Diabetic cardiomyopathy (DCM) is one of the common complications of diabetic patients,
which can induce myocardial hypertrophy, cardiac fibrosis, and heart failure. Growing …
which can induce myocardial hypertrophy, cardiac fibrosis, and heart failure. Growing …
Role of AMP-activated protein kinase on cardio-metabolic abnormalities in the development of diabetic cardiomyopathy: a molecular landscape
Cardiovascular complications associated with diabetes mellitus remains a leading cause of
morbidity and mortality across the world. Diabetic cardiomyopathy is a descriptive pathology …
morbidity and mortality across the world. Diabetic cardiomyopathy is a descriptive pathology …
[HTML][HTML] Gut microbiota interactions with anti-diabetic medications and pathogenesis of type 2 diabetes mellitus
Microorganisms including bacteria, viruses, protozoa, and fungi living in the gastrointestinal
tract are collectively known as the gut microbiota. Dysbiosis is the imbalance in microbial …
tract are collectively known as the gut microbiota. Dysbiosis is the imbalance in microbial …
Heterogeneity of antidiabetic treatment effect on the risk of major adverse cardiovascular events in type 2 diabetes: a systematic review and meta-analysis
Background We explored whether clinically relevant baseline characteristics of patients with
type 2 diabetes can modify the effect of glucagon-like peptide-1 receptor agonists (GLP-1 …
type 2 diabetes can modify the effect of glucagon-like peptide-1 receptor agonists (GLP-1 …
Antidiabetic effect of a flavonoid-rich extract from Sophora alopecuroides L. in HFD-and STZ-induced diabetic mice through PKC/GLUT4 pathway and regulating …
Y Lv, P Zhao, K Pang, Y Ma, H Huang, T Zhou… - Journal of …, 2021 - Elsevier
Headings ethnopharmacological relevance Sophora alopecuroides L. is a traditional
ethnopharmacological plant, which is widely used in traditional Chinese medicine and …
ethnopharmacological plant, which is widely used in traditional Chinese medicine and …
[HTML][HTML] Programmed death of cardiomyocytes in cardiovascular disease and new therapeutic approaches
K Cai, H Jiang, Y Zou, C Song, K Cao, S Chen… - Pharmacological …, 2024 - Elsevier
Cardiovascular diseases (CVDs) have a complex pathogenesis and pose a major threat to
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …
[HTML][HTML] Glimepiride and metformin combinations in diabetes comorbidities and complications: real-world evidence
Objective To evaluate the usage of various strengths of glimepiride and metformin fixed-
dose combinations in the management of type 2 diabetes mellitus (T2DM) patients with …
dose combinations in the management of type 2 diabetes mellitus (T2DM) patients with …