Toward understanding the origin and evolution of cellular organisms
M Kanehisa - Protein Science, 2019 - Wiley Online Library
In this era of high‐throughput biology, bioinformatics has become a major discipline for
making sense out of large‐scale datasets. Bioinformatics is usually considered as a practical …
making sense out of large‐scale datasets. Bioinformatics is usually considered as a practical …
[HTML][HTML] Gene set analysis: challenges, opportunities, and future research
Gene set analysis methods are widely used to provide insight into high-throughput gene
expression data. There are many gene set analysis methods available. These methods rely …
expression data. There are many gene set analysis methods available. These methods rely …
The Gene Ontology resource: enriching a GOld mine
Nucleic acids research, 2021 - academic.oup.com
Abstract The Gene Ontology Consortium (GOC) provides the most comprehensive resource
currently available for computable knowledge regarding the functions of genes and gene …
currently available for computable knowledge regarding the functions of genes and gene …
[HTML][HTML] The genecards suite
The GeneCards® database of human genes was launched in 1997 and has expanded
since then to encompass gene-centric, disease-centric, and pathway-centric entities and …
since then to encompass gene-centric, disease-centric, and pathway-centric entities and …
[HTML][HTML] Information fusion as an integrative cross-cutting enabler to achieve robust, explainable, and trustworthy medical artificial intelligence
Medical artificial intelligence (AI) systems have been remarkably successful, even
outperforming human performance at certain tasks. There is no doubt that AI is important to …
outperforming human performance at certain tasks. There is no doubt that AI is important to …
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
Proximity labeling in mammalian cells with TurboID and split-TurboID
This protocol describes the use of TurboID and split-TurboID in proximity labeling
applications for mapping protein–protein interactions and subcellular proteomes in live …
applications for mapping protein–protein interactions and subcellular proteomes in live …
Identification of common genetic risk variants for autism spectrum disorder
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
Species-level functional profiling of metagenomes and metatranscriptomes
Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
[HTML][HTML] Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
AC Aschenbrenner, M Mouktaroudi, B Krämer… - Genome medicine, 2021 - Springer
Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …