Although beneficial in acute and chronic pain management, the use of local anaesthetics is
limited by its duration of action and the dose dependent adverse effects on the cardiac and …

Intrathecal midazolam binds with gamma aminobutyric acid-A receptors in the spinal cord
leading to an analgesic effect. Clinical studies suggested that intrathecal midazolam may …

Background Despite recent systematic reviews suggesting their benefit for postoperative
nausea, vomiting, or both (PONV) prevention, benzodiazepines have not been incorporated …

Background: Previous clinical and experimental studies have shown that a midazolam-
clonidine mixture has a synergistic antinociceptive effect. This study evaluated the …

Purpose Several studies have applied lumbar spinal anesthesia (SA) with
isobaric/hyperbaric bupivacaine and opioids in elective laparoscopic cholecystectomy (LC) …

Purpose Few studies have described segmental thoracic spinal anesthesia (STSA) as
primary anesthesiologic method in breast and axillary surgery, documenting the association …

Spinal anaesthesia, which is one of the techniques for infraumbilical surgeries, is most
commonly criticized for limited duration of postoperative analgesia. Several adjuvants have …

Background Limited studies have applied thoracic continuous spinal anesthesia in
abdominal surgery, relying exclusively on opioids. This retrospective study analyzes 2 …

Background: Dexmedetomidine and midazolam both modulate spinal analgesia by different
mechanisms, and yet, no human studies are available to compare them for postoperative …

Background Intrathecal adjuncts have been used to prolong the quality and duration of
subarachnoid anaesthesia. Midazolam given intrathecally is reported to have …