Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …

Tissue factor (TF) is the high-affinity receptor and cofactor for factor (F) VII/VIIa. The TF-FVIIa
complex is the primary initiator of blood coagulation and plays an essential role in …

The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment
and care, but cardiovascular disease (CVD) still remains an important clinical problem, since …

Antiphospholipid antibodies (Abs) are associated with thrombosis and are a risk factor for
recurrent pregnancy loss and obstetric complications in patients with the antiphospholipid …

Objective To study the intracellular mechanism involved in the up‐regulation of tissue factor
(TF) on endothelial cells (ECs) by antiphospholipid antibodies (aPL), we examined the …

Women with antiphospholipid antibodies (aPL) are at risk of adverse pregnancy outcomes,
including recurrent first-trimester pregnancy loss and late pregnancy complications such as …

Antiphospholipid antibodies (aPL) promote endothelial dysfunction, inflammation and
procoagulant state. We investigated the effect of hydroxychloroquine (HCQ) on …

Objective To characterize the binding and functional properties of antiphospholipid
antibodies (aPL) induced by immunization with a viral peptide and to determine whether …

The case report in this review illustrates an acute myocardial infarction in a young adult
probably due to arterial thrombosis that can be attributed to a hypercoagulable state …

Increasing evidence suggests that autoantibodies directly contribute to hypercoagulability in
the antiphospholipid syndrome (APS). One proposed mechanism is the antibody-induced …