Leishmaniases are vector-borne parasitic diseases with 0.9–1.4 million new human cases
each year worldwide. In the vectorial part of the life-cycle, Leishmania development is …

The microbiota of Anopheles mosquitoes interferes with mosquito infection by Plasmodium
and influences mosquito fitness, therefore affecting vectorial capacity. This natural barrier to …

Malaria transmission-blocking vaccines (TBVs) target the development of Plasmodium
parasites within the mosquito, with the aim of preventing malaria transmission from one …

The sexual phase of the malaria pathogen, Plasmodium falciparum, culminates in
fertilization within the midgut of the mosquito and represents a crucial step in the completion …

The continued global burden of malaria can in part be attributed to a complex lifecycle, with
both human hosts and mosquito vectors serving as transmission reservoirs. In preclinical …

Despite decades of effort battling against malaria, the disease is still a major cause of
morbidity and mortality. Transmission-blocking vaccines (TBVs) that target sexual stage …

Gene drives for mosquito population replacement are promising tools for malaria control.
However, there is currently no clear pathway for safely testing such tools in endemic …

Eukaryotic parasites and pathogens continue to cause some of the most detrimental and
difficult to treat diseases (or disease states) in both humans and animals, while also …

The idea of malaria transmission-blocking vaccines (TBVs) surfaced more than two decades
ago. Since then, the research paradigm focused on developing TBVs that target surface …

The mosquito gut microbiota is vital to the proper functioning of the host organism.
Mosquitoes may benefit from this microbiota in their guts because it promotes factors …