Anti‐vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity

MJ Sankar, J Sankar, P Chandra - Cochrane Database of …, 2018 - cochranelibrary.com
Background Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis in
foetal life. Researchers have recently attempted to use anti‐VEGF agents for the treatment of …

Systemic and ocular safety of intravitreal anti-VEGF therapies for ocular neovascular disease

M Tolentino - Survey of ophthalmology, 2011 - Elsevier
The treatment of ocular neovascular diseases is being revolutionized by intravitreal
therapies targeting vascular endothelial growth factor (VEGF). Two agents are approved for …

Effect of intravitreal aflibercept vs laser photocoagulation on treatment success of retinopathy of prematurity: the FIREFLEYE randomized clinical trial

A Stahl, EA Sukgen, WC Wu, D Lepore, H Nakanishi… - Jama, 2022 - jamanetwork.com
Importance Laser photocoagulation, which is the standard treatment for retinopathy of
prematurity (ROP), can have adverse events. Studies of anti–vascular endothelial growth …

Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures

OM Tepper, RD Galiano, JM Capla, C Kalka… - Circulation, 2002 - Am Heart Assoc
Background—The recent discovery of circulating endothelial progenitor cells (EPCs) has
altered our understanding of new blood vessel growth such as occurs during collateral …

The role of vascular endothelial growth factor in ocular health and disease

AP Adamis, DT Shima - Retina, 2005 - journals.lww.com
The leading causes of blindness are retinal and choroidal diseases manifesting abnormal
vessel permeability and growth. Scientists have sought to understand the mechanisms …

Müller cell‐derived VEGF is a significant contributor to retinal neovascularization

Y Bai, J Ma, J Guo, J Wang, M Zhu… - The Journal of …, 2009 - Wiley Online Library
Vascular endothelial growth factor (VEGF-A) is a major pathogenic factor and a therapeutic
target for age-related macular degeneration, diabetic retinopathy, and retinopathy of …

Retinopathy of prematurity: recent advances in our understanding

CM Wheatley, JL Dickinson, DA Mackey… - British Journal of …, 2002 - bjo.bmj.com
Retinopathy of prematurity (ROP) has been recognised as an important cause of childhood
visual impairment and blindness since the 1940s when improved facilities and treatment …

Pathogenesis and treatment of bronchopulmonary dysplasia

J Gien, JP Kinsella - Current opinion in pediatrics, 2011 - journals.lww.com
Pathogenesis and treatment of bronchopulmonary dysplasia : Current Opinion in Pediatrics
Pathogenesis and treatment of bronchopulmonary dysplasia : Current Opinion in Pediatrics …

High or low oxygen saturation and severe retinopathy of prematurity: a meta-analysis

ML Chen, L Guo, LEH Smith, CEL Dammann… - …, 2010 - publications.aap.org
CONTEXT: Low oxygen saturation appears to decrease the risk of severe retinopathy of
prematurity (ROP) in preterm newborns when administered during the first few weeks after …

Hypoxia-inducible factor-1 (HIF-1): a potential target for intervention in ocular neovascular diseases

R Krishna Vadlapatla, A Dutt Vadlapudi… - Current drug …, 2013 - ingentaconnect.com
Constant oxygen supply is essential for proper tissue development, homeostasis and
function of all eukaryotic organisms. Cellular response to reduced oxygen levels is mediated …