Side effects of acetazolamide: a systematic review and meta-analysis assessing overall risk and dose dependence

CN Schmickl, RL Owens, JE Orr… - BMJ open …, 2020 - bmjopenrespres.bmj.com
Introduction Acetazolamide (AZM) is used for various conditions (eg, altitude sickness, sleep
apnoea, glaucoma), but therapy is often limited by its side effect profile. Our objective was to …

Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs

VHN Estrada, DM Franco, RD Medina… - Cochrane Database …, 2017 - cochranelibrary.com
Background High altitude illness (HAI) is a term used to describe a group of cerebral and
pulmonary syndromes that can occur during travel to elevations above 2500 metres (8200 …

[HTML][HTML] Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials

RI Horowitz, PR Freeman - Medical hypotheses, 2020 - Elsevier
Purpose Asymptomatic or minimally symptomatic infection with COVID-19 can result in silent
transmission to large numbers of individuals, resulting in expansion of the pandemic with a …

Effect of nocturnal oxygen and acetazolamide on exercise performance in patients with pre-capillary pulmonary hypertension and sleep-disturbed breathing …

S Ulrich, S Keusch, FF Hildenbrand… - European heart …, 2015 - academic.oup.com
Aim Sleep-disturbed breathing (SDB) is common in pre-capillary pulmonary hypertension
(PH) and impairs daytime performance. In lack of proven effective treatments, we tested …

New insights into carbonic anhydrase inhibition, vasodilation, and treatment of hypertensive-related diseases

ER Swenson - Current hypertension reports, 2014 - Springer
Carbonic anhydrase (CA) and its inhibitors are relevant to many physiological processes
and diseases. The enzyme is differentially expressed throughout the body, in concentration …

Long-term monitoring of oxygen saturation at altitude can be useful in predicting the subsequent development of moderate-to-severe acute mountain sickness

G Mandolesi, G Avancini, M Bartesaghi… - Wilderness & …, 2014 - Elsevier
Objective The use of pulse oximetry (Sp o 2) to identify subjects susceptible to acute
mountain sickness (AMS) is the subject of debate. To obtain more reliable data, we …

[HTML][HTML] Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

CR Morris, HY Kim, J Wood, JB Porter, ES Klings… - …, 2013 - ncbi.nlm.nih.gov
Pulmonary hypertension is a common but often overlooked complication associated with
thalassemia syndromes. There are limited data on the safety and efficacy of selective …

Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs

AG Gonzalez Garay, D Molano Franco… - Cochrane Database …, 1996 - cochranelibrary.com
Background High altitude illness (HAI) is a term used to describe a group of mainly cerebral
and pulmonary syndromes that can occur during travel to elevations above 2500 metres (˜ …

Interventions for preventing high altitude illness: Part 3. Miscellaneous and non‐pharmacological interventions

D Molano Franco, VH Nieto Estrada… - Cochrane Database …, 1996 - cochranelibrary.com
Background High altitude illness (HAI) is a term used to describe a group of mainly cerebral
and pulmonary syndromes that can occur during travel to elevations above 2500 metres (˜ …

Ventilatory oscillations at exercise: effects of hyperoxia, hypercapnia, and acetazolamide

E Hermand, FJ Lhuissier, J Larribaut… - Physiological …, 2015 - Wiley Online Library
Periodic breathing has been found in patients with heart failure and sleep apneas, and in
healthy subjects in hypoxia, during sleep and wakefulness, at rest and, recently, at exercise …