[HTML][HTML] Therapeutic potential of mesenchymal stem/stromal cells (MSCs)-based cell therapy for inflammatory bowel diseases (IBD) therapy

MJ Saadh, MV Mikhailova, S Rasoolzadegan… - European Journal of …, 2023 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) therapy has become an emerging
therapeutic modality for the treatment of inflammatory bowel disease (IBD), given their …

[HTML][HTML] Therapeutic Potential of Bioactive Components from Scutellaria baicalensis Georgi in Inflammatory Bowel Disease and Colorectal Cancer: A Review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2023 - mdpi.com
Scutellaria baicalensis Georgi (SBG), an herbal medicine with various biological activities,
including anti-inflammatory, anticancer, antiviral, antibacterial, and antioxidant activities, is …

[HTML][HTML] Treatment effects of natural products on inflammatory bowel disease in vivo and their mechanisms: Based on animal experiments

Y Zhou, D Wang, W Yan - Nutrients, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory disease of the
intestine that can be classified as ulcerative colitis (UC) and Crohn's disease (CD) …

Construction of Wogonin Nanoparticle‐Containing Strontium‐Doped Nanoporous Structure on Titanium Surface to Promote Osteoporosis Fracture Repair

D Wang, MW Chen, YJ Wei, WB Geng… - Advanced …, 2022 - Wiley Online Library
M2 polarization of macrophage is an important immunomodulatory event that attenuates
inflammation. To regulate the immune microenvironment in osteoporotic conditions for …

Immunotherapy of inflammatory bowel disease (IBD) through mesenchymal stem cells

H Huldani, R Margiana, F Ahmad… - International …, 2022 - Elsevier
Many pathophysiologic pathways and immune-pathologic etiologies are addressed as
Inflammatory bowel disease (IBD) causes. Moreover, dysfunction of the immune system …

Targeted therapy of spinal cord injury: inhibition of apoptosis is a promising therapeutic strategy

W He, Z Li, H Gu, Q Pan, F Lin - Molecular Neurobiology, 2024 - Springer
Spinal cord injury (SCI) is a serious disabling central nervous system injury that can lead to
motor, sensory, and autonomic dysfunction below the injury level. SCI can be divided into …

[HTML][HTML] The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming

J Chen, S Xie, D Qiu, M Xie, M Wu, X Li, X Zhang… - Journal of Advanced …, 2023 - Elsevier
Introduction Numerous studies demonstrated that NLRP3 has been implicated in the
pathogenesis of inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) …

[HTML][HTML] Jianpi-Qingchang decoction alleviates ulcerative colitis by modulating endoplasmic reticulum stress-related autophagy in intestinal epithelial cells

D Qiao, X Liu, Y Zhang, Z Zhang, Y Tang… - Biomedicine & …, 2023 - Elsevier
Endoplasmic reticulum stress (ERS)-related autophagy is involved in the occurrence and
development of ulcerative colitis (UC). Therefore, regulating ERS-related autophagy is a …

Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury

W Shao, C Zhang, K Li, Z Lu, Z Zhao, K Gao, C Lv - Brain Research, 2022 - Elsevier
Spinal cord injury (SCI) is a complex central traumatic disease. STAT3 signal transduction
pathway plays an important role in SCI. Wogonin has been reported to exhibit …

Restoration of Motor and Bladder Functions after Spinal Cord Injury via Sustained Wogonin Release from Carbon Nanotube Incorporated Hydrogels

Q Zhang, L Zhang, W Weng, X Qiu, Y Zhuang… - ACS Materials …, 2024 - ACS Publications
Spinal cord injury (SCI) results in structural and neural cell damage, leading to motor and
bladder dysfunction. The limited regenerative capabilities and SCI-mediated inflammation …