Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …

Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …

Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …

Drug resistance diagnostics that rely on the detection of resistance-related mutations could
expedite patient care and TB eradication. We perform minimum inhibitory concentration …

Antibiotic resistance is one of the biggest threats to human health globally. Alarmingly,
multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis have now …

Featured Application This comprehensive overview of drug-resistant tuberculosis will be
useful for researchers to expand their knowledge beyond mechanisms other than …

Eighty years after the introduction of the first antituberculosis (TB) drug, the treatment of drug-
susceptible TB remains very cumbersome, requiring the use of four drugs (isoniazid …

The sensitivity of Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB), to
antibiotic prodrugs is dependent on the efficacy of the activation process that transforms the …

Mycobacterium tuberculosis (Mtb) killed more people in 2017 than any other single
infectious agent. This dangerous pathogen is able to withstand stresses imposed by the …

The Mycobacterium tuberculosis genome is more heterogenous and less genetically stable
within the host than previously thought. Currently, only limited data exist on the within-host …