Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led
to an increasing interest in the development and optimization of drug-delivery systems …

The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Nanoemulsions are considered as the most promising solution to improve the delivery of
ophthalmic drugs. The design of ophthalmic nanoemulsions requires an extensive …

Nanoemulsions are liquid-in-liquid dispersion with a droplet size of about 100 nm. They
have a transparent appearance, high rate of bioavailability, and increased shelf life …

Over the last years, the scientific interest about topical ocular delivery targeting the posterior
segment of the eye has been increasing. This is probably due to the fact that this is a non …