Tissue injury, hypoxia and significant metabolic stress activate innate immune responses
driven by tumor necrosis factor (TNF)-α and other proinflammatory cytokines that typically …

Many disease processes activate a cellular stress response that initiates a cascade of
inflammation and damage. However, this process also triggers a tissue protection and repair …

In this study, we investigated the effects and mechanism of quercetin preconditioning on anti-
myocardial ischemia reperfusion (IR) injuries in vivo. Meanwhile, their potential anti …

Quercetin (Que), a plant-derived flavonoid, has multiple benefical actions on the
cardiovascular system. The current study investigated whether Que postconditioning has …

Aim Renal ischaemia‐reperfusion (I/R) injury, a primary cause of acute renal failure, can
induce high morbidity and mortality. This study aimed to explore the effect of erythropoietin …

Object Carbamylated erythropoietin (CEPO) is a modified erythropoietin molecule that does
not affect hematocrit. In this study, the authors compared the efficacy of a single dose with a …

Erythropoietin (EPO) has been well recognized as a tissue protective agent by inhibiting
apoptosis and inflammation. The tissue protective effect of EPO, however, only occurs at a …

It is now recognized that in addition to its activity upon erythroid progenitor cells,
erythropoietin (Epo) is capable of stimulating survival of different non-erythroid cells. Since …

Ischemia/reperfusion injury (IRI) commonly occurs in renal transplantation. Erythropoietin
(EPO) exerts a protective effect in IRI. To investigate the underlying molecular mechanism …

Alzheimer's disease (AD) is a debilitating neurodegenerative disease, characterized by
extracellular deposition of senile plaques, mostly amyloid β-protein (Aβ) and neuronal loss …