Peroxisome proliferator–activated receptor α (PPAR α) is a nuclear receptor of clinical
interest as a drug target in various metabolic disorders. PPAR α also exhibits marked anti …

Inappropriate, excessive or uncontrolled inflammation contributes to a range of human
diseases. Inflammation involves a multitude of cell types, chemical mediators and …

A variety of fatty acids exists in the diet of humans, in the bloodstream of humans, and in
cells and tissues of humans. Fatty acids are energy sources and membrane constituents …

Inflammation is a condition which contributes to a range of human diseases. It involves a
multitude of cell types, chemical mediators, and interactions. Eicosapentaenoic acid (EPA) …

In mammalian cells, two cellular organelles, mitochondria and peroxisomes, share the ability
to degrade fatty acid chains. Although each organelle harbors its own fatty acid β-oxidation …

Associations between per-and polyfluoroalkyl substances (PFASs) and increased blood
lipids have been repeatedly observed in humans, but a causal relation has been debated …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n‐3 fatty acids found in
oily fish and fish oil supplements. These fatty acids are able to inhibit partly a number of …

Abstract The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription
factor that plays a major role in metabolic regulation. This review addresses the functional …

Autophagy is an evolutionarily conserved catabolic process that recycles nutrients upon
starvation and maintains cellular energy homeostasis,,. Its acute regulation by nutrient …

Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …