Heterocyclic Schiff base transition metal complexes in antimicrobial and anticancer chemotherapy

MA Malik, OA Dar, P Gull, MY Wani, AA Hashmi - MedChemComm, 2018 - pubs.rsc.org
In recent years, the number of people suffering from cancer and multidrug-resistant
infections has sharply increased, leaving humanity without any choice but to search for new …

A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases

W Zafar, SH Sumrra, ZH Chohan - European journal of medicinal chemistry, 2021 - Elsevier
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

A review on the antimicrobial assessment of triazole-azomethine functionalized frameworks incorporating transition metals

W Zafar, M Ashfaq, SH Sumrra - Journal of Molecular Structure, 2023 - Elsevier
Antimicrobial resistance is a growing threat to global public health that calls for innovative
strategies to develop new methods of action against resistance to emerging infectious …

Facile synthesis, spectroscopic evaluation and antimicrobial screening of metal endowed triazole compounds

SH Sumrra, W Zafar, H Javed, M Zafar, MZ Hussain… - Biometals, 2021 - Springer
The scientific interest in developing new complexes as inhibitors of bacterial biofilm related
infections is constantly rising. The present work describes the chemical synthesis, structural …

A review on the efficacy and medicinal applications of metal-based triazole derivatives

SH Sumrra, U Habiba, W Zafar, M Imran… - Journal of …, 2020 - Taylor & Francis
Recently, there has been increased microbial and multidrug resistance in clinical field that
negatively affects health because it leads to a variety of diseases due to inefficient mode of …

Schiff base metallodrugs in antimicrobial and anticancer chemotherapy applications: a comprehensive review

S Shekhar, AM Khan, S Sharma, B Sharma, A Sarkar - Emergent Materials, 2022 - Springer
The proliferation in cancer and multidrug-resistant infections amidst personage with the
evolution of civilization is an alarming bone of contention. Cancer has long been the pre …

Metal complexes—a promising approach to target biofilm associated infections

R Olar, M Badea, MC Chifiriuc - Molecules, 2022 - mdpi.com
Microbial biofilms are represented by sessile microbial communities with modified gene
expression and phenotype, adhered to a surface and embedded in a matrix of self-produced …

The synthesis of a Cu (ii) Schiff base complex using a bidentate N 2 O 2 donor ligand: crystal structure, photophysical properties, and antibacterial activities

Y Guo, X Hu, X Zhang, X Pu, Y Wang - RSC advances, 2019 - pubs.rsc.org
In this paper, a new mononuclear Cu (II) complex was synthesized by using a bidentate
N2O2 Schiff base ligand,(E)-2-bromo-4-chloro-6-[(2, 6-dimethylphenylimino) methyl] phenol …

[HTML][HTML] Pharmacological aspects of Co (II), Ni (II) and Cu (II) schiff base complexes: An insight

S Gautam, R Kumar, P Singh, N Gandhi, P Jain - Results in Chemistry, 2023 - Elsevier
Schiff bases are versatile chemical compounds that are frequently utilized and manufactured
by reacting various amines with carbonyl compounds (aldehydes/ketones), resulting in the …

Synthesis, spectroscopic characterization, molecular docking, and evaluation of antibacterial potential of transition metal complexes obtained using triazole chelating …

NS Al-Radadi, EM Zayed, GG Mohamed… - Journal of …, 2020 - Wiley Online Library
Mononuclear chelates of Ni (II), Co (II), Fe (III), Cd (II), and Cu (II) derived from triazole novel
tridentate ligands were prepared and characterized by different spectroscopic methods. The …