Esophageal cancer (EC) is a disease often marked by aggressive growth and poor
prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant …

Abstract Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer
development. IL-32 gene consists of eight small exons, and IL-32 mRNA has nine …

Large-scale genomic studies have identified multiple somatic aberrations in breast cancer,
including copy number alterations and point mutations. Still, identifying causal variants and …

Metastasis is the leading cause of breast cancer–related deaths. Cancer-associated
fibroblasts (CAFs), the predominant stromal cell type in the breast tumour microenvironment …

Objective: The aim of this study was to the determine impact of severe esophageal
anastomotic leak (SEAL) upon long-term survival and locoregional cancer recurrence …

Background Metastasis is the leading cause of mortality in human cancers, including
esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was …

LL-37 is a C-terminal peptide proteolytically released from 18 kDa human cathelicidin
protein (hCAP18). Chronic infections, inflammation, tissue injury and tissue regeneration are …

IL-32 is a multifaceted cytokine associated with several diseases and inflammatory
conditions. Its expression is induced in response to cellular stress such as hypoxia …

Purpose: The proinflammatory cytokine interleukin-32 (IL-32) is a novel tumor marker highly
expressed in various human carcinomas, including gastric cancer. However, its effects on …

PYCR1 exerts an important role in various cancers, but its effect on colorectal cancer (CRC)
and the potential mechanism remain to be clarified. In this study, we aimed to explore the …