Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

A revamped interest in the study of hallucinogens has recently emerged, especially with
regard to their potential application in the treatment of psychiatric disorders. In the last …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Schizophrenia remains a major health burden, highlighting the need for new treatment
approaches. We consider the potential for targeting the trace amine (TA) system. We first …

Lysergic acid diethylamide (LSD) is a serotonergic psychedelic compound receiving
increasing interest due to putative anxiolytic and antidepressant properties. However, the …

Background Although clozapine is an effective option for treatment-resistant schizophrenia
(TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main …

LSD is an ambiguous substance, said to mimic psychosis and to improve mental health in
people suffering from anxiety and depression. Little is known about the neuronal correlates …

Neurotrophic factors are a family of growth factors that modulate cellular growth, survival,
and differentiation. For many decades, it has been generally believed that a lack of …

Rationale Previous research demonstrating that lysergic acid diethylamide (LSD) produces
alterations in time perception has implications for its impact on conscious states and a range …

Schizophrenia is a widespread psychiatric disorder that affects 0.5–1.0% of the world's
population and induces significant, long-term disability that exacts high personal and …