[HTML][HTML] Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the …

CF Kirkpatrick, JP Bolick, PM Kris-Etherton… - Journal of clinical …, 2019 - Elsevier
Abstract Historically, low-carbohydrate (CHO) and very-low-CHO diets have been used for
weight loss. Recently, these diets have been promoted for type 2 diabetes (T2D) …

Gene and cell therapy approaches for familial hypercholesterolemia: An update

N Parsamanesh, O Kooshkaki, H Siami, RD Santos… - Drug discovery today, 2023 - Elsevier
Highlights•FH is a common inherited autosomal codominant disorder.•Homozygous FH
patients usually have a poor response to traditional lipid-lowering therapy.•We reviewed the …

Hidden Burden of Electronic Health Record‐Identified Familial Hypercholesterolemia: Clinical Outcomes and Cost of Medical Care

P Patel, Y Hu, A Kolinovsky, Z Geng… - Journal of the …, 2019 - Am Heart Assoc
Background Familial hypercholesterolemia (FH), is a historically underdiagnosed,
undertreated, high‐risk condition that is associated with a high burden of cardiovascular …

Estimated Prevalence of Heterozygous Familial Hypercholesterolemia in Patients With Acute Coronary Syndrome Multicenter Registration Study in Japan

H Ohmura, Y Fukushima, A Mizuno, K Niwa… - International Heart …, 2017 - jstage.jst.go.jp
Heterozygous familial hypercholesterolemia (FH) represents a strong risk for development of
premature coronary artery disease (CAD). However, the majority of patients with FH are …

Type of LDLR Mutation and the Pharmacogenetics of Familial Hypercholesterolemia Treatment

PCJL Santos, AC Pereira - Pharmacogenomics, 2015 - Taylor & Francis
Familial hypercholesterolemia (FH) is an autosomal dominant disease mainly caused by
mutations in the low-density lipoprotein receptor (LDLR) gene. FH patients present a wide …

Efficiency and problems of statin therapy in patients with heterozygous familial hypercholesterolemia

V Korneva, T Kuznetsova, U Julius - Atherosclerosis Supplements, 2019 - Elsevier
Familial hypercholesterolemia (FH) is associated with a very high risk of cardiovascular
complications and the need for an early aggressive lipid-lowering therapy. The achievement …

Screening and advanced lipid phenotyping in familial hypercholesterolemia: The Very Large Database of Lipids Study-17 (VLDL-17)

PE Miller, SS Martin, PP Toth, RD Santos… - Journal of clinical …, 2015 - Elsevier
Background Familial hypercholesterolemia (FH) is an autosomal dominant dyslipidemia
characterized by defective low-density lipoprotein (LDL) clearance. The aim of this study …

Early diagnosis and treatment of familial hypercholesterolemia

JC Elkins, S Fruh - The Nurse Practitioner, 2019 - journals.lww.com
If undiagnosed and untreated, familial hypercholesterolemia can lead to serious cardiac
complications, such as premature atherosclerotic cardiovascular disease. NPs should be …

Hypercholestérolémie familiale peu diagnostiquée, insuffisamment traitée. Enquête auprès de 495 médecins.

S Béliard, JP Rabès, B Cariou, M Farnier, M Krempf… - La Presse Médicale, 2018 - Elsevier
Résumé Introduction L'hypercholestérolémie familiale hétérozygote (HF) est l'une des
maladies génétiques les plus fréquentes avec une incidence de l'ordre de 1/250. Elle est …

Hypercholestérolémie familiale: un risque cardiovasculaire largement sous-estimé

J Ferrières, É Bruckert, S Béliard, JP Rabès… - Annales de Cardiologie …, 2018 - Elsevier
Résumé Contexte L'hypercholestérolémie familiale est une dyslipidémie héréditaire
monogénique (autosomique dominante) caractérisée par une augmentation permanente et …