The simultaneous measurement of multiple modalities represents an exciting frontier for
single-cell genomics and necessitates computational methods that can define cellular states …

The success of immune checkpoint therapy in cancer has changed our way of thinking,
promoting the design of future cancer treatments that places the immune system at the …

Cancer is a leading cause of death worldwide. Understanding the functional mechanisms
associated with metabolic reprogramming, which is a typical feature of cancer cells, is key to …

Human NK cells are usually defined as CD3-CD56+ lymphocytes. However, a CD56-CD16+
(CD56neg) lymphocyte population that displays NK-associated markers expands during …

Dengue infection is caused by the dengue virus (DENV) and is transmitted to humans by
infected female Aedes aegypti and Aedes albopictus mosquitoes. There are nearly 100 …

The latent HIV-1 reservoir represents a major barrier to achieving a long-term antiretroviral
therapy (ART)-free remission or cure for HIV-1. Natural Killer (NK) cells are innate immune …

Immunosuppression increases the risk of nosocomial infection in patients with chronic
critical illness. This exploratory study aimed to determine the immunometabolic signature …

Natural killer (NK) cells are among the first responders to viral infections. The ability of NK
cells to rapidly recognize and kill virally infected cells is regulated by their expression of …

Natural killer (NK) cells respond rapidly in early HIV-1 infection. HIV-1 prevention and
control strategies harnessing NK cells could be enabled by mechanistic understanding of …

Dengue infection is caused by the Dengue virus (DENV) and is transmitted to humans by
infected female Aedes aegypti and Aedes albopictus mosquitoes. There are nearly 100 …