Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, ie, the
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …

Here we contrast several carcinogenesis models. The somatic-mutation-theory posits
mutations as main causes of malignancy. However, inconsistencies led to alternative …

Breast cancer development and progression are believed to be a sequential process, from
normal to hyperplastic, to in situ, and to invasive and metastatic stages. Given that over 90 …

The intention of this Special Issue is to elucidate the role of apoptosis and cellular
senescence in different pathological processes, such as cancer and aging. Apoptosis and …

Cordycepin, or 3′-deoxyadenosine, is an adenosine analog with a broad spectrum of
biological activity. The key structural difference between cordycepin and adenosine lies in …

Objectives Irreversible Electroporation (IRE) is a non-thermal minimally invasive cancer
therapy used in the treatment of liver tumors. However, the therapy entails an electrical …

The immunogenicity of cemiplimab, a fully human immunoglobulin G4 monoclonal antibody
directed against programmed cell death 1, was assessed in patients across multiple tumor …

Cervical intraepithelial neoplasia (CIN) is the development of abnormal cells on the surface
of the cervix, caused by a human papillomavirus (HPV) infection. Although in most of the …

Introduction Worry about cancer recurrence is identified as the most common psychological
burdens experienced by cancer patients and survivors. The present study aimed to …

There is an urgent need to develop new therapies for cancer treatment due to high rates of
resistance and tumor relapse. Moreover, chemotherapy and radiation weaken the immune …