Binding site identification of G protein-coupled receptors through a 3D Zernike polynomials-based method: application to C. elegans olfactory receptors
Studying the binding processes of G protein-coupled receptors (GPCRs) proteins is of
particular interest both to better understand the molecular mechanisms that regulate the …
particular interest both to better understand the molecular mechanisms that regulate the …
Prediction of GPCR‐Ligand Binding Using Machine Learning Algorithms
We propose a novel method that predicts binding of G‐protein coupled receptors (GPCRs)
and ligands. The proposed method uses hub and cycle structures of ligands and amino acid …
and ligands. The proposed method uses hub and cycle structures of ligands and amino acid …
Tyrosine Kinase Ligand‐Receptor Pair Prediction by Using Support Vector Machine
M Yarimizu, C Wei, Y Komiyama, K Ueki… - Advances in …, 2015 - Wiley Online Library
Receptor tyrosine kinases are essential proteins involved in cellular differentiation and
proliferation in vivo and are heavily involved in allergic diseases, diabetes, and …
proliferation in vivo and are heavily involved in allergic diseases, diabetes, and …
ReLiance: a machine learning and literature-based prioritization of receptor—ligand pairings
E Iacucci, LC Tranchevent, D Popovic… - …, 2012 - academic.oup.com
Motivation: The prediction of receptor—ligand pairings is an important area of research as
intercellular communications are mediated by the successful interaction of these key …
intercellular communications are mediated by the successful interaction of these key …
Identifying Ligand-Receptor Interactions via an Integrated Fuzzy Model
Background: The ligand-receptor interaction plays an important role in signal transduction
required for cellular differentiation, proliferation, and immune response process. The …
required for cellular differentiation, proliferation, and immune response process. The …
Predicting Potential Ligands for Orphan GPCRs Based on the Improved Laplacian Regularized Least Squares Method
Y Yan, X Shao, Z Jiang - … Conference, ICIC 2014, Taiyuan, China, August …, 2014 - Springer
Predicting potential interactions between receptors and ligands can provide important clues
to the discovery of ligands for orphan GPCRs (oGPCRs). In this paper, we develop an …
to the discovery of ligands for orphan GPCRs (oGPCRs). In this paper, we develop an …