Stroke is one of the leading causes of death and disability worldwide. However, there is a
lack of effective medications to speed up the recovery process. Ischemic stroke, as the result …

Sox1, Sox2 and Sox3, the three members of the SoxB1 subgroup of transcription factors,
have similar sequences, expression patterns and overexpression phenotypes. Thus, it has …

How have animals evolved new body designs (morphological evolution)? This requires
explanations both for simple morphological changes, such as differences in pigmentation …

Although there is much evidence showing functional relationship between Hedgehog
pathway, in particular Sonic hedgehog, and SOX transcription factors during embryonic …

Sex-determining region Y is a crucial gene that initiates male sex determination in
mammals. Mutations of the Sp1-binding site in the 5′ flanking region of SRY are associated …

Sox genes participate in several developmental processes, including sex determination and
differentiation. In this study, the genomic structure of sox17 was characterized in the sea …

Background Mechanisms of glioma invasion remain to be fully elucidated. Glioma cells
within glioblastoma multiforme (GBM) range from well-differentiated tumor cells to less …

Background Esophageal squamous cell carcinoma (ESCC) is a lethal malignancy lacking
valid prognostic biomarkers. As a member of the High Mobility Group domain-containing …

The transcriptional regulation of neural stem/progenitor cells (NS/PCs) is of great interest in
neural development and stem cell biology. The RNA-binding protein Musashi1 (Msi1), which …

Ovarian cancer is one of the most common cancers which cause female mortality. The
knowledge of ovarian cancer initiation and progression is critical to develop new therapeutic …