Pathophysiological mechanisms implicated in postpartum depression

JL Payne, J Maguire - Frontiers in neuroendocrinology, 2019 - Elsevier
This review aims to summarize the diverse proposed pathophysiological mechanisms
contributing to postpartum depression, highlighting both clinical and basic science research …

Perinatal depression—the fourth inflammatory morbidity of pregnancy?: theory and literature review

LM Osborne, C Monk - Psychoneuroendocrinology, 2013 - Elsevier
Perinatal depression is one of the leading causes of maternal morbidity and mortality. The
biological etiology of this disorder remains in question, despite considerable research into …

[HTML][HTML] Antenatal depression programs cortisol stress reactivity in offspring through increased maternal inflammation and cortisol in pregnancy: The Psychiatry …

S Osborne, A Biaggi, TE Chua, A Du Preez… - …, 2018 - Elsevier
Introduction Antenatal depression is associated with a broad range of suboptimal outcomes
in offspring, although the underlying mechanisms are not yet understood. Animal studies …

Inflammatory cytokines and prenatal depression: Is there a mediating role of maternal gut microbiota?

Q Fang, Y Tu, X Fan, T Zang, N Wu, T Qiu, Y Li… - Journal of Psychiatric …, 2023 - Elsevier
Objective The mechanism of levels of inflammatory cytokines that affects brain function and
mood through gut microbiota has not been fully elucidated. This study aimed to investigate …

Perinatal major depression biomarkers: a systematic review

M Serati, M Redaelli, M Buoli, AC Altamura - Journal of affective disorders, 2016 - Elsevier
Postpartum depression, now termed perinatal depression by the DSM-5, is a clinically
relevant disorder reaching 15% of incidence. Although it is quite frequent and associated …

[HTML][HTML] Pre-pregnancy obesity is associated with greater systemic inflammation and increased risk of antenatal depression

L Sominsky, M O'Hely, K Drummond, S Cao… - Brain, Behavior, and …, 2023 - Elsevier
Background Pre-pregnancy obesity is an emerging risk factor for perinatal depression.
However, the underlying mechanisms remain unclear. We investigated the association …

The immune system and the role of inflammation in perinatal depression

P Leff-Gelman, I Mancilla-Herrera, M Flores-Ramos… - Neuroscience …, 2016 - Springer
Major depression during pregnancy is a common psychiatric disorder that arises from a
complex and multifactorial etiology. Psychosocial stress, sex, hormones, and genetic …

Vitamin E for the management of major depressive disorder: Possible role of the anti-inflammatory and antioxidant systems

LM Manosso, A Camargo, AL Dafre… - Nutritional …, 2022 - Taylor & Francis
Objectives Vitamin E has various functions in humans, including antioxidant, anti-
inflammatory, anti-cancer, and anti-atherogenic actions, as well as direct effects on …

Prenatal inflammation and neurodevelopment in schizophrenia: a review of human studies

BJ Miller, N Culpepper, MH Rapaport… - Progress in Neuro …, 2013 - Elsevier
A confluence of evidence supports an association between prenatal inflammation and risk of
schizophrenia. Outside of studies of prenatal infections and risk of schizophrenia, other …

Stress-induced inflammatory responses in women: effects of race and pregnancy

LM Christian, R Glaser, K Porter… - Psychosomatic medicine, 2013 - journals.lww.com
Objective African Americans experience preterm birth at nearly twice the rate of whites.
Chronic stress associated with minority status is implicated in this disparity. Inflammation is a …