[PDF][PDF] Covid‐19 and liver injury: role of inflammatory endotheliopathy, platelet dysfunction, and thrombosis
MJ McConnell, R Kondo, N Kawaguchi… - Hepatology …, 2022 - Wiley Online Library
Liver injury, characterized predominantly by elevated aspartate aminotransferase and
alanine aminotransferase, is a common feature of coronavirus disease 2019 (COVID‐19) …
alanine aminotransferase, is a common feature of coronavirus disease 2019 (COVID‐19) …
[HTML][HTML] Disease-drug and drug-drug interaction in COVID-19: Risk and assessment
COVID-19 is announced as a global pandemic in 2020. Its mortality and morbidity rate are
rapidly increasing, with limited medications. The emergent outbreak of COVID-19 prompted …
rapidly increasing, with limited medications. The emergent outbreak of COVID-19 prompted …
[HTML][HTML] Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
[HTML][HTML] Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
SARS-CoV-2 infection has been shown to trigger a wide spectrum of immune responses
and clinical manifestations in human hosts. Here, we sought to elucidate novel aspects of …
and clinical manifestations in human hosts. Here, we sought to elucidate novel aspects of …
[HTML][HTML] Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection
Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …
disease. These drugs have not consistently demonstrated high efficacy in preventing or …
[HTML][HTML] Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs
OA Badary - The pharmacogenomics journal, 2021 - nature.com
The outbreak of Coronavirus disease 2019 (COVID-19) has evolved into an emergent global
pandemic. Many drugs without established efficacy are being used to treat COVID-19 …
pandemic. Many drugs without established efficacy are being used to treat COVID-19 …
[HTML][HTML] ADME and pharmacokinetic properties of remdesivir: its drug interaction potential
S Deb, AA Reeves, R Hopefl, R Bejusca - Pharmaceuticals, 2021 - mdpi.com
On 11 March 2020, the World Health Organization (WHO) classified the Coronavirus
Disease 2019 (COVID-19) as a global pandemic, which tested healthcare systems …
Disease 2019 (COVID-19) as a global pandemic, which tested healthcare systems …
[HTML][HTML] Liver injury induced by COVID 19 treatment–what do we know?
The severity of coronavirus disease 2019 (COVID-19) may be correlated with the risk of liver
injury development. An increasing number of studies indicate that degrees of hepatotoxicity …
injury development. An increasing number of studies indicate that degrees of hepatotoxicity …
[HTML][HTML] Pharmacogenetics and precision medicine approaches for the improvement of COVID-19 therapies
M Biswas, N Sawajan, T Rungrotmongkol… - Frontiers in …, 2022 - frontiersin.org
Many drugs are being administered to tackle coronavirus disease 2019 (COVID-19)
pandemic situations without establishing clinical effectiveness or tailoring safety. A …
pandemic situations without establishing clinical effectiveness or tailoring safety. A …
COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics
D Tworowski, A Gorohovski, S Mukherjee… - Nucleic acids …, 2021 - academic.oup.com
The recent outbreak of COVID-19 has generated an enormous amount of Big Data. To date,
the COVID-19 Open Research Dataset (CORD-19), lists∼ 130,000 articles from the WHO …
the COVID-19 Open Research Dataset (CORD-19), lists∼ 130,000 articles from the WHO …