[HTML][HTML] Acute kidney injury: definition, pathophysiology and clinical phenotypes

K Makris, L Spanou - The clinical biochemist reviews, 2016 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a clinical syndrome that complicates the course and worsens the
outcome in a significant number of hospitalised patients. Recent advances in clinical and …

The gut-liver-kidney axis: Novel regulator of fatty liver associated chronic kidney disease

D Raj, B Tomar, A Lahiri, SR Mulay - Pharmacological research, 2020 - Elsevier
Increased interest in understanding the liver-kidney axis in health and disease during the
last decade unveiled multiple recent evidence that suggested a strong association of fatty …

Hepatorenal syndrome: the clinical impact of vasoactive therapy

I Colle, PF Laterre - Expert Review of Gastroenterology & …, 2018 - Taylor & Francis
Introduction: Hepatorenal syndrome (HRS) is a unique form of acute kidney injury seen in
cirrhotic patients and associated with significant mortality and morbidity. Despite its impact …

Renohepatic crosstalk: does acute kidney injury cause liver dysfunction?

K Lane, JJ Dixon, IAM MacPhee… - Nephrology dialysis …, 2013 - academic.oup.com
The concept of hepatorenal syndrome is well recognized, although incompletely
understood. The converse clinical problem of hepatic dysfunction in patients with acute …

[HTML][HTML] Hepatorenal syndrome: Update on diagnosis and treatment

O Baraldi, C Valentini, G Donati, G Comai… - World journal of …, 2015 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a common complication in patients with end-stage liver disease
and advanced cirrhosis regardless of the underlying cause. Hepatorenal syndrome (HRS), a …

Update on hepatorenal syndrome: definition, pathogenesis, and management

E Habas, AR Ibrahim, MO Moursi, BA Shraim… - Arab Journal of …, 2022 - Elsevier
Hepatorenal syndrome (HRS) is acute kidney injury (AKI) that occurs without evidence of
structural abnormalities in the kidneys in patients with liver disease. It is thought to be due to …

Development of an automated phenotyping algorithm for hepatorenal syndrome

JD Koola, SE Davis, O Al-Nimri, SK Parr… - Journal of biomedical …, 2018 - Elsevier
Abstract Objective Hepatorenal Syndrome (HRS) is a devastating form of acute kidney injury
(AKI) in advanced liver disease patients with high morbidity and mortality, but phenotyping …

Bridging organ transcriptomics for advancing multiple organ toxicity assessment with a generative AI approach

T Li, X Chen, W Tong - npj Digital Medicine, 2024 - nature.com
Translational research in toxicology has significantly benefited from transcriptomic profiling,
particularly in drug safety. However, its application has predominantly focused on limited …

Prevalence and short-term outcome of hepatorenal syndrome: A 9-year experience in a high-complexity hospital in Colombia

M Rey R, AF Delgado, A De Zubiria, R Pinto… - PLoS …, 2020 - journals.plos.org
Background & aims Hepatorenal syndrome is a rare entity that is part of the complications of
liver cirrhosis in its more severe stages. Without treatment, its mortality rate increases …

Total C-21 Steroidal Glycosides From Baishouwu Ameliorate Hepatic and Renal Fibrosis by Regulating IL-1β/MyD88 Inflammation Signaling

T Qin, M Wang, T Zhang, Y Wang, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Fibrosis is a worldwide public health problem, which typically results from chronic diseases
and often leads to organ malfunction. Chronic inflammation has been suggested to be the …