The Hedyotis diffusa Willd. (Rubiaceae): A Review on Phytochemistry, Pharmacology, Quality Control and Pharmacokinetics

R Chen, J He, X Tong, L Tang, M Liu - Molecules, 2016 - mdpi.com
Hedyotis diffusa Willd (H. diffusa) is a well-known Chinese medicine with a variety of
activities, especially its anti-cancer effect in the clinic. Up to now, 171 compounds have been …

[HTML][HTML] Antitumor potential of Hedyotis diffusa Willd: a systematic review of bioactive constituents and underlying molecular mechanisms

X Han, X Zhang, Q Wang, L Wang, S Yu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cancer is a major cause of death in the world. Chemotherapy can extend the life of cancer
patients to some extent, but the quality of life is reduced. Therefore, the quest for more …

Anti-inflammatory naphthoates and anthraquinones from the roots of Morinda officinalis

H Luo, Y Wang, Q Qin, Y Wang, J Xu, X He - Bioorganic Chemistry, 2021 - Elsevier
Morinda (Morinda officinalis) is widely consumed as a health-care herb in Asia and reported
to possess various biological activities. In this study, anti-inflammatory phytochemicals were …

A combination index and glycoproteomics-based approach revealed synergistic anticancer effects of curcuminoids of turmeric against prostate cancer PC3 cells

MM Wei, SJ Zhao, XM Dong, YJ Wang, C Fang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Herbal medicines (HMs) often exert integration
effects, including synergistic, additive and antagonistic effects, in such ways that they act on …

Scutellaria barbata and Hedyotis diffusa herb pair for breast cancer treatment: Potential mechanism based on network pharmacology

TT Ma, GL Zhang, CF Dai, BR Zhang, KX Cao… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance The Scutellaria barbata and Hedyotis diffusa (SH)
herb pair is extensively used in Traditional Chinese Medicine for efficacy enhancement in …

Simultaneous determination of fourteen compounds of Hedyotis diffusa Willd extract in rats by UHPLC–MS/MS method: Application to pharmacokinetics and tissue …

X Chen, P Zhu, B Liu, L Wei, Y Xu - Journal of pharmaceutical and …, 2018 - Elsevier
A rapid, sensitive and selective ultra high-performance liquid chromatography-tandem mass
spectrometry UHPLC–MS/MS method has been developed and validated for the …

Complementary Chinese herbal medicine therapy improves survival of patients with gastric cancer in Taiwan: a nationwide retrospective matched-cohort study

KF Hung, CP Hsu, JH Chiang, HJ Lin, YT Kuo… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Many patients with gastric cancer seek traditional
medicine consultations in Asian countries. This study aimed to investigate the prescription of …

Exploring the mechanisms of anti-ovarian cancer of Hedyotis diffusa Willd and Scutellaria barbata D. Don through focal adhesion pathway

X Xu, F Chen, L Zhang, L Liu, C Zhang, Z Zhang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Hedyotis diffusa Willd and Scutellaria barbata D.
Don (HD-SB) pairing were widely used as traditional medicine known for their anti-tumor …

Prescription patterns of Chinese herbal products for post-surgery colon cancer patients in Taiwan

TH Chao, PK Fu, CH Chang, SN Chang, FC Mao… - Journal of …, 2014 - Elsevier
Abstract Ethno-pharmacological relevance Traditional Chinese medicine (TCM) is
commonly provided to cancer patients, however, the patterns of prescriptions for this type of …

Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation

V Fattori, FA Pinho-Ribeiro, SM Borghi… - Inflammation …, 2015 - Springer
Objective This study aimed at evaluating the activity of curcumin in superoxide anion-
induced pain-like behavior and leukocyte recruitment in mice. Treatment Administration of …