Glioma stem-like cells and metabolism: potential for novel therapeutic strategies
A Harland, X Liu, M Ghirardello, MC Galan… - Frontiers in …, 2021 - frontiersin.org
Glioma stem-like cells (GSCs) were first described as a population which may in part be
resistant to traditional chemotherapeutic therapies and responsible for tumour regrowth …
resistant to traditional chemotherapeutic therapies and responsible for tumour regrowth …
Recent advances in the use of lipid-based nanoparticles against glioblastoma multiforme
B Ortega-Berlanga, C Gonzalez… - Archivum Immunologiae et …, 2021 - Springer
Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults.
Although the overall incidence is less than 10 per 100,000 individuals, its poor prognosis …
Although the overall incidence is less than 10 per 100,000 individuals, its poor prognosis …
TOOme: a novel computational framework to infer cancer tissue-of-origin by integrating both gene mutation and expression
Metastatic cancers require further diagnosis to determine their primary tumor sites. However,
the tissue-of-origin for around 5% tumors could not be identified by routine medical …
the tissue-of-origin for around 5% tumors could not be identified by routine medical …
[HTML][HTML] A machine learning framework to trace tumor tissue-of-origin of 13 types of cancer based on DNA somatic mutation
Carcinoma of unknown primary (CUP), defined as metastatic cancers with unknown cancer
origin, occurs in 3‐5 per 100 cancer patients in the United States. Heterogeneity and …
origin, occurs in 3‐5 per 100 cancer patients in the United States. Heterogeneity and …
Isocitrate dehydrogenase (IDH) 1/2 mutations as prognostic markers in patients with glioblastomas
JR Chen, Y Yao, HZ Xu, ZY Qin - Medicine, 2016 - journals.lww.com
Isocitrate Dehydrogenase (IDH)1/2 Mutations as Prognostic Ma... : Medicine Isocitrate
Dehydrogenase (IDH)1/2 Mutations as Prognostic Markers in Patients With Glioblastomas …
Dehydrogenase (IDH)1/2 Mutations as Prognostic Markers in Patients With Glioblastomas …
A potent blood–brain barrier-permeable mutant IDH1 inhibitor suppresses the growth of glioblastoma with IDH1 mutation in a patient-derived orthotopic xenograft …
Y Machida, M Nakagawa, H Matsunaga… - Molecular cancer …, 2020 - AACR
Gliomas are the second most common primary brain tumors in adults. They are treated with
combination therapies, including surgery, radiotherapy, and chemotherapy. There are …
combination therapies, including surgery, radiotherapy, and chemotherapy. There are …
Survival in patients with glioblastoma at a first progression does not correlate with isocitrate dehydrogenase (IDH)1 gene mutation status
Y Tabei, K Kobayashi, K Saito, S Shimizu… - Japanese journal of …, 2021 - academic.oup.com
Backgrounds Mutations in the isocitrate dehydrogenase (IDH) 1 gene are favourable
prognostic factors in newly diagnosed diffuse gliomas, whereas it remains controversial in …
prognostic factors in newly diagnosed diffuse gliomas, whereas it remains controversial in …
Short‐echo three‐dimensional H‐1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels
Background The purpose of this study was to evaluate the feasibility of using a short echo
time, three‐dimensional H‐1 magnetic resonance spectroscopic imaging (MRSI) sequence …
time, three‐dimensional H‐1 magnetic resonance spectroscopic imaging (MRSI) sequence …
Imaging tumor metabolism using in vivo magnetic resonance spectroscopy
Y Li, I Park, SJ Nelson - The Cancer Journal, 2015 - journals.lww.com
Magnetic resonance spectroscopy (MRS) is a powerful tool for noninvasively investigating
normal and abnormal metabolism. When used in combination with imaging strategies …
normal and abnormal metabolism. When used in combination with imaging strategies …
EGFR, p53, IDH-1 and MDM2 immunohistochemical analysis in glioblastoma: therapeutic and prognostic correlation
RM Montgomery, LS Queiroz, F Rogerio - Arquivos de neuro …, 2015 - SciELO Brasil
We studied 36 glioblastoma cases at HC-UNICAMP from 2008 to 2012 and classified the
immunohistochemical distribution of the wild-type epidermal growth factor receptor (EGFR) …
immunohistochemical distribution of the wild-type epidermal growth factor receptor (EGFR) …