Elevated protein synthesis is an important feature of many cancer cells and often arises as a
consequence of increased signaling flux channeled to eukaryotic initiation factor 4F (eIF4F) …

Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and
have been demonstrated to be very successful in combating viral infections in clinic …

Traditional functions of DExD/H-box helicases are concerned with RNA metabolism; they
have been shown to play a part in nearly every cellular process that involves RNA. On the …

Introduction: Rhodanine-based compounds have been associated with numerous biological
activities. After many years of research in drug discovery, they have gained a reputation as …

Recently, inhibition effects of enzymes such as acetylcholinesterase (AChE) and carbonic
anhydrase (CA) has appeared as a promising approach for pharmacological intervention in …

The DEAD-box RNA helicase DDX3 is a multifunctional protein involved in all aspects of
RNA metabolism, including transcription, splicing, mRNA nuclear export, translation, RNA …

COVID-19 is currently a highly pressing health threat and therapeutic strategies to mitigate
the infection impact are urgently needed. Characterization of the SARS-CoV-2 interactome …

DDX3 belongs to the DEAD‐box proteins, a large family of ATP‐dependent RNA helicases
that participate in all aspects of RNA metabolism. Human DDX3 is a component of several …

Cancer is one of the most studied areas of human biology over the past century. Despite
having attracted much attention, hype, and investments, the search to find a cure for cancer …

The innate immune response to viruses is critical for the correct establishment of protective
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …