Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of
Alzheimer's disease and other dementias. More recent use is for myasthenia gravis. Many of …

Butyrylcholinesterase is a promiscuous enzyme that displays complex kinetic behavior. It is
toxicologically important because it detoxifies organophosphorus poisons (OP) by making a …

Metabolic activation of pesticides in the liver may result in highly reactive intermediates
capable of impairing various cellular functions. Nevertheless, the knowledge about the effect …

Organophosphorus agents (OPs) are irreversible inhibitors of acetylcholinesterase (AChE).
OP poisoning causes major cholinergic syndrome. Current medical counter-measures …

Bioscavengers are an effective alternative approach for pre-and post-exposure treatments of
nerve agent (NA) poisoning. Bioscavengers are natural or recombinant enzymes, reactive …

In this study, the effects of sublethal concentrations of the carbamate carbaryl on the
cholinesterase (ChE) and carboxylesterase (CES) activities present in the oligochaete …

Organophosphorus compounds (OPs) are neurotoxic molecules developed as pesticides
and chemical warfare nerve agents (CWNAs). Most of them are covalent inhibitors of …

Organophosphate insecticides (OPs) continue to be an important class of agrochemicals
used in modern agriculture worldwide. Even though these pesticides persist in the …

In vitro inhibition data of cholinesterases (ChEs) and reactivation with HI 6 are presented for
separated VX and VR enantiomers with high purity (enantiomer excess> 99.999%) …

Poisoning by nerve agents via the percutaneous (pc) route is an issue because the slow
absorption of agent could result in poisoning which outlasts the protection provided by …