Metal-catalyzed approaches toward the oxindole core

AD Marchese, EM Larin, B Mirabi… - Accounts of Chemical …, 2020 - ACS Publications
Conspectus The oxindole scaffold is a privileged structural motif that is found in a variety of
bioactive targets and natural products. Moreover, derivatives of the oxindole structure are …

Recent advances in fixation of CO2 into organic carbamates through multicomponent reaction strategies

L Wang, C Qi, W Xiong, H Jiang - Chinese Journal of Catalysis, 2022 - Elsevier
Carbon dioxide (CO 2) is the main greenhouse gas and also an ideal C1 feedstock in
organic synthesis because it is abundant, non-toxic, nonflammable, and renewable. The …

Nickel‐Catalyzed Asymmetric Reductive Carbo‐Carboxylation of Alkenes with CO2

XW Chen, JP Yue, K Wang, YY Gui, YN Niu… - Angewandte …, 2021 - Wiley Online Library
Reductive carboxylation of organo (pseudo) halides with CO2 is a powerful method to
provide carboxylic acids quickly. Notably, the catalytic reductive carbo‐carboxylation of …

P, N Ligand in Ni-Catalyzed Cross-Coupling Reactions: A Promising Tool for π-Functionalization

J Bae, EJ Cho - ACS Catalysis, 2023 - ACS Publications
Bidentate P, N ligands, integrating phosphine and nitrogen donors, are highlighted for their
versatile characteristics, offering both electronic and steric tunability. Their hemilabile nature …

Quinim: a new ligand scaffold enables nickel-catalyzed enantioselective synthesis of α-alkylated γ-lactam

X Wu, J Qu, Y Chen - Journal of the American Chemical Society, 2020 - ACS Publications
Herein, we report a nickel-catalyzed reductive cross-coupling reaction of easily accessible 3-
butenyl carbamoyl chloride with primary alkyl iodide to access the chiral α-alkylated …

An insight into the advanced synthetic recipes to access ubiquitous indole heterocycles

BS Mathada, NG Yernale, JN Basha, J Badiger - Tetrahedron Letters, 2021 - Elsevier
Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …

2-Oxindole and related heterocycles: synthetic methodologies for their natural products and related derivatives

S Sharma, Y Monga, A Gupta, S Singh - RSC advances, 2023 - pubs.rsc.org
Natural goods, medications, and pharmaceutically active substances all contain substituted
oxindoles. Generally, the C-3 stereocenter of the substituents of oxindoles and their absolute …

Three-component visible-light-induced palladium-catalyzed 1, 2-alkyl carbamoylation/cyanation of alkenes

X Jia, Z Zhang, V Gevorgyan - ACS catalysis, 2021 - ACS Publications
A mild visible-light-induced Pd-catalyzed one-pot three-component alkyl-carbamoylation
and cyanation of alkenes was developed. This general transformation, which proceeds via …

Photo‐Excited Nickel‐Catalyzed Silyl‐Radical‐Mediated Direct Activation of Carbamoyl Chlorides To Access (Hetero) aryl Carbamides

S Maiti, S Roy, P Ghosh, A Kasera… - Angewandte Chemie, 2022 - Wiley Online Library
Amide bonds connect the amino acids in proteins and exist as a prevalent structural motif in
biomolecules. Herein, we have exploited the concept of cross‐electrophile coupling by …

Carbamoyl fluoride-enabled enantioselective Ni-catalyzed carbocarbamoylation of unactivated alkenes

Y Li, FP Zhang, RH Wang, SL Qi… - Journal of the American …, 2020 - ACS Publications
Carbamoyl Fluoride-Enabled Enantioselective Ni-Catalyzed Carbocarbamoylation of
Unactivated Alkenes | Journal of the American Chemical Society ACS ACS Publications …