The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

Many cancers have long been thought to primarily metabolize glucose for energy production—
a phenomenon known as the Warburg Effect, after the classic studies of Otto Warburg in the …

AMPK is a metabolic sensor that helps maintain cellular energy homeostasis. Despite
evidence linking AMPK with tumor suppressor functions, the role of AMPK in tumorigenesis …

The discovery of microRNAs (miRNAs) almost two decades ago established a new
paradigm of gene regulation. During the past ten years these tiny non-coding RNAs have …

Ribosomal protein S6 (RPS6) is a component of the 40S small ribosomal subunit and
participates in the control of mRNA translation. Additionally, phospho (p)-RPS6 has been …

Glioblastoma (GB) is the most frequent and aggressive primary tumor of the central nervous
system. Prognosis remains poor despite ongoing progress. In cases where the gadolinium …

Glioblastoma is the most common and most aggressive primary brain tumor. Despite
maximum treatment, patients only have a median survival time of 15 months, because of the …

MicroRNAs (miRNAs) in body fluids are candidate diagnostics for a variety of conditions and
diseases, including breast cancer. One premise for using extracellular miRNAs to diagnose …

The AMP-activated protein kinase (AMPK) is a central regulator of cellular metabolism and
energy homeostasis in mammalian tissues. Pertinent to cancer biology is the fact that AMPK …

Glioblastoma is one of the most devastating cancers, in which tumor cell infiltration into
surrounding normal brain tissue confounds clinical management. This review describes …