The extracellular matrix (ECM) is a critical regulator of neural network development and
plasticity. As neuronal circuits develop, the ECM stabilizes synaptic contacts, while its …

The matrix metalloproteinases and related A disintegrin and metalloproteinase enzymes are
implicated in various diseases of the nervous system. However, metalloproteinases are …

Magnetic nanoparticles (MNPs) have shown great promise for use as tools in a wide variety
of biomedical applications, some of which require the delivery of large numbers of MNPs …

Biofabrication techniques have endeavored to improve the regeneration of the peripheral
nervous system (PNS), but nothing has surpassed the performance of current clinical …

Temporal lobe epilepsy (TLE) is a devastating disease in which aberrant synaptic plasticity
plays a major role. We identify matrix metalloproteinase (MMP) 9 as a novel synaptic …

It has been 50years since Gross and Lapiere discovered collagenolytic activity during
tadpole tail metamorphosis, which was later on revealed as MMP-1, the founding member of …

The fibrous scar that develops after central nervous system (CNS) injury is considered a
major impediment for axonal regeneration. It consists of a dense collagen IV meshwork …

Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced hours after
injury to peripheral nerve. This study shows that MMP-9 gene deletion and neutralization …

Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced in Schwann
cells hours after peripheral nerve injury and controls axonal degeneration and macrophage …

Nerve injuries can be life-long debilitating traumas that severely impact patients' quality of
life. While many acellular neural scaffolds have been developed to aid the process of nerve …