Sex differences in anxiety and depression: circuits and mechanisms

DA Bangasser, A Cuarenta - Nature Reviews Neuroscience, 2021 - nature.com
Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

Novel electrode technologies for neural recordings

G Hong, CM Lieber - Nature Reviews Neuroscience, 2019 - nature.com
Neural recording electrode technologies have contributed considerably to neuroscience by
enabling the extracellular detection of low-frequency local field potential oscillations and …

[HTML][HTML] Breathing coordinates cortico-hippocampal dynamics in mice during offline states

N Karalis, A Sirota - Nature communications, 2022 - nature.com
Network dynamics have been proposed as a mechanistic substrate for the information
transfer across cortical and hippocampal circuits. However, little is known about the …

The theory of constructed emotion: an active inference account of interoception and categorization

LF Barrett - Social cognitive and affective neuroscience, 2017 - academic.oup.com
The science of emotion has been using folk psychology categories derived from philosophy
to search for the brain basis of emotion. The last two decades of neuroscience research …

[HTML][HTML] Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …

[HTML][HTML] Brainstem circuits for locomotion

R Leiras, JM Cregg, O Kiehn - Annual review of neuroscience, 2022 - annualreviews.org
Locomotion is a universal motor behavior that is expressed as the output of many integrated
brain functions. Locomotion is organized at several levels of the nervous system, with …

Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning

ME Bouton, S Maren, GP McNally - Physiological reviews, 2021 - journals.physiology.org
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …

Near-atomic model of microtubule-tau interactions

EH Kellogg, NMA Hejab, S Poepsel, KH Downing… - Science, 2018 - science.org
Tau is a developmentally regulated axonal protein that stabilizes and bundles microtubules
(MTs). Its hyperphosphorylation is thought to cause detachment from MTs and subsequent …

Resolving the neural circuits of anxiety

GG Calhoon, KM Tye - Nature neuroscience, 2015 - nature.com
Although anxiety disorders represent a major societal problem demanding new therapeutic
targets, these efforts have languished in the absence of a mechanistic understanding of this …

[HTML][HTML] The parabrachial nucleus: CGRP neurons function as a general alarm

RD Palmiter - Trends in neurosciences, 2018 - cell.com
The parabrachial nucleus (PBN), which is located in the pons and is dissected by one of the
major cerebellar output tracks, is known to relay sensory information (visceral malaise, taste …