[HTML][HTML] Sex differences in tryptophan metabolism: A systematic review focused on neuropsychiatric disorders

ML Pais, J Martins, M Castelo-Branco… - International Journal of …, 2023 - mdpi.com
Tryptophan (Tryp) is an essential amino acid and the precursor of several neuroactive
compounds within the central nervous system (CNS). Tryp metabolism, the common …

[HTML][HTML] Probiotics-based treatment as an integral approach for alcohol use disorder in alcoholic liver disease

C Fuenzalida, MS Dufeu, J Poniachik… - Frontiers in …, 2021 - frontiersin.org
Alcoholic liver disease (ALD) is one of the leading causes of morbidity among adults with
alcohol use disorder (AUD) worldwide. Its clinical course ranges from steatosis to alcoholic …

GDNF gene therapy for alcohol use disorder in male non-human primates

MM Ford, BE George, VS Van Laar, KM Holleran… - Nature medicine, 2023 - nature.com
Alcohol use disorder (AUD) exacts enormous personal, social and economic costs globally.
Return to alcohol use in treatment-seeking patients with AUD is common, engendered by a …

Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence

F Alasmari, S Goodwani, RE McCullumsmith… - Progress in …, 2018 - Elsevier
Emerging evidence demonstrates that alcohol dependence is associated with dysregulation
of several neurotransmitters. Alterations in dopamine, glutamate and gamma-aminobutyric …

Therapeutic potential of ketamine for alcohol use disorder

SD Worrell, TJ Gould - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Excessive alcohol consumption is involved in 1/10 of deaths of US working-age adults and
costs the country around $250,000,000 yearly. While Alcohol Use Disorder (AUD) pathology …

Therapeutic mechanisms of classic hallucinogens in the treatment of addictions: from indirect evidence to testable hypotheses

MP Bogenschutz, JM Pommy - Drug testing and analysis, 2012 - Wiley Online Library
Alcohol and drug addiction are major public health problems, and existing treatments are
only moderately effective. Although there has been interest for over half a century in the …

Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol

A Stewart, B Maity, SP Anderegg… - Proceedings of the …, 2015 - National Acad Sciences
Alcohol is the most commonly abused drug worldwide, and chronic alcohol consumption is a
major etiological factor in the development of multiple pathological sequelae, including …

[HTML][HTML] Is there a shared neurobiology between aggression and Internet addiction disorder?

C Hahn, DJ Kim - Journal of behavioral addictions, 2014 - akjournals.com
Purpose: Evidences indicate that Internet addiction disorder (IAD) has a higher risk of
developing aggression and violent behavior. A few correlation studies between IAD and …

[HTML][HTML] Associations between classic psychedelics and nicotine dependence in a nationally representative sample

G Jones, J Lipson, MK Nock - Scientific Reports, 2022 - nature.com
Tobacco use is the single largest cause of preventable death worldwide, but none of the
established treatments aimed at smoking cessation work for a majority of smokers. As such …

[HTML][HTML] Biomarkers of Affective Dysregulation Associated with In Utero Exposure to EtOH

N Darbinian, N Merabova, G Tatevosian, M Morrison… - Cells, 2023 - mdpi.com
Introduction: Children with fetal alcohol spectrum disorders (FASD) exhibit behavioral and
affective dysregulation, including hyperactivity and depression. The mechanisms are not …