Fabrication of smart tantalum carbide MXene quantum dots with intrinsic immunomodulatory properties for treatment of allograft vasculopathy
A Rafieerad, W Yan, KN Alagarsamy… - Advanced Functional …, 2021 - Wiley Online Library
MXene nanomaterials have sparked significant interest among interdisciplinary researchers
to tackle today's medical challenges. In particular, colloidal MXene quantum dots (MQDs) …
to tackle today's medical challenges. In particular, colloidal MXene quantum dots (MQDs) …
[HTML][HTML] Immunoengineered MXene nanosystem for mitigation of alloantigen presentation and prevention of transplant vasculopathy
MXenes are an emerging class of nanomaterials with significant potential for applications in
nanomedicine. Amongst MXene technologies, titanium carbide (Ti 3 C 2 T x) nanomaterials …
nanomedicine. Amongst MXene technologies, titanium carbide (Ti 3 C 2 T x) nanomaterials …
Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7
Background—Heart transplantation is a lifesaving procedure for patients with end-stage
heart failure. Despite much effort and advances in the field, current immunosuppressive …
heart failure. Despite much effort and advances in the field, current immunosuppressive …
Pediatric coronary allograft vasculopathy—a review of pathogenesis and risk factors
KR Schumacher, RJ Gajarski… - Congenital Heart …, 2012 - Wiley Online Library
Coronary allograft vasculopathy is the current leading cause for late graft loss following
cardiac transplantation. Its pathogenesis is multifactorial, including immune, constitutional …
cardiac transplantation. Its pathogenesis is multifactorial, including immune, constitutional …
Disruption of the gut microbiota with antibiotics exacerbates acute vascular rejection
K Rey, S Manku, W Enns, T Van Rossum… - …, 2018 - journals.lww.com
Background The gut microbiota influences many immunological processes but how its
disruption affects transplant rejection is poorly understood. Methods Interposition grafting of …
disruption affects transplant rejection is poorly understood. Methods Interposition grafting of …
Natural killer cells play a critical role in cardiac allograft vasculopathy in an interleukin-6–dependent manner
ZX Zhang, X Huang, J Jiang, D Lian, W Min… - …, 2014 - journals.lww.com
Background Approximately 50% of cardiac transplants fail in the long term, and currently,
there are no specific treatments to prevent chronic rejection. In the clinic, donor cardiac graft …
there are no specific treatments to prevent chronic rejection. In the clinic, donor cardiac graft …
Cytomegalovirus chemokine receptor M33 knockout reduces chronic allograft rejection in a murine aortic transplant model
NM Fritz, T Stamminger, M Ramsperger-Gleixner… - Transplant …, 2021 - Elsevier
Background Numerous studies suggest that cytomegalovirus (CMV) infection may act as
isolated risk factor in the development of cardiac allograft vasculopathy (CAV). Viral G …
isolated risk factor in the development of cardiac allograft vasculopathy (CAV). Viral G …
MicroRNA-155 promotes the directional migration of resident smooth muscle progenitor cells by regulating monocyte chemoattractant protein 1 in transplant …
Y Sun, K Wang, P Ye, J Wu, L Ren… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Smooth muscle–like cells are major cell components of transplant
arteriosclerosis lesions. This study investigated the origin of the smooth muscle–like cells …
arteriosclerosis lesions. This study investigated the origin of the smooth muscle–like cells …
Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy
JJ Devitt, CL King, TDG Lee… - Journal of cardiothoracic …, 2011 - Springer
Background Ischemia/reperfusion induced innate immune injury is inescapable in solid
organ transplantation. Prolonged cold ischemia exacerbates the primary manifestation of …
organ transplantation. Prolonged cold ischemia exacerbates the primary manifestation of …
First case of donor transmitted non-leukemic promyelocytic sarcoma
T Williams, OS Aljitawi, R Moussa, S McHugh… - Leukemia & …, 2012 - Taylor & Francis
Malignancy after solid organ or stem cell transplant can occur in three distinct ways: de
novo, recurrent in the recipient, or transmission from donor to recipient [1]. According to an …
novo, recurrent in the recipient, or transmission from donor to recipient [1]. According to an …