Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

Breast cancer is the most common malignancy in women worldwide. Metastasis is the
leading cause of high mortality in most cancers. Although predicting the early stage of breast …

Protein methylation, a post-translational modification (PTM), is observed in a wide variety of
cell types from prokaryotes to eukaryotes. With recent and rapid advancements in epigenetic …

Cancer arises from a multitude of disorders resulting in loss of differentiation and a stem cell-
like phenotype characterized by uncontrolled growth. Polycomb Group (PcG) proteins are …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Tumor vasculature is characterized by aberrant structure and function, resulting in immune
suppressive profiles of tumor microenvironment (TME) through limiting immune cell …

Abstract Protein arginine methyltransferase 2 (PRMT2) is involved in several biological
processes via histone methylation and transcriptional regulation. Although PRMT2 has been …

Abstract Protein arginine methyltransferase 1 (PRMT1) is able to promote breast cancer cell
proliferation. However, the detailed mechanisms of PRMT1-mediated breast cancer cell …

Epigenetic modifications play important roles during the pathogenesis of multiple myeloma
(MM). Herein, we found that protein arginine methyltransferase 1 (PRMT1) was highly …

Enhancer of zeste homolog 2 (EZH2), as a main component of Polycomb Repressive
Complex 2, catalyzes histone H3K27me3 to silence its target gene expression. EZH2 …