Recent Advances in Nanomechanical Measurements and Their Application for Pharmaceutical Crystals
MK Mishra, P Mahur, P Manimunda… - Molecular …, 2023 - ACS Publications
Mechanical behavior of pharmaceutical crystals directly impacts the formulation
development and manufacturing of drug products. The understanding of crystal structure …
development and manufacturing of drug products. The understanding of crystal structure …
Nanomechanical testing in drug delivery: Theory, applications, and emerging trends
Mechanical properties play a central role in drug formulation development and
manufacturing. Traditional characterization of mechanical properties of pharmaceutical …
manufacturing. Traditional characterization of mechanical properties of pharmaceutical …
Elastic molecular crystals: From serendipity to design to applications
The mechanical adaptiveness of long-range ordered molecular crystals has long been
ignored due to their brittle nature, unlike polymers and flexible biomaterials. However, the …
ignored due to their brittle nature, unlike polymers and flexible biomaterials. However, the …
Structural basis for mechanical anisotropy in polymorphs of a caffeine–glutaric acid cocrystal
Insights into structure–mechanical property correlations in molecular and multicomponent
crystals have recently attracted significant attention owing to their practical applications in …
crystals have recently attracted significant attention owing to their practical applications in …
Structural analysis of elastically bent organic crystals using in situ indentation and micro-Raman spectroscopy
The structural dynamics of two elastically bendable, halogenated N-benzylideneaniline
organic crystals were studied using an in situ three-point bending test and Raman …
organic crystals were studied using an in situ three-point bending test and Raman …
Indentation plasticity and fracture studies of organic crystals
S Mannepalli, KSRN Mangalampalli - Crystals, 2017 - mdpi.com
This review article summarizes the recent advances in measuring and understanding the
indentation-induced plastic deformation and fracture behavior of single crystals of a wide …
indentation-induced plastic deformation and fracture behavior of single crystals of a wide …
Probing stress induced phase transformation in aspirin polymorphs using Raman spectroscopy enabled nanoindentation
Nanoindentation has extensively been used to measure the mechanical properties of
molecular crystals. However, the possibilities of stress induced polymorphic transformation …
molecular crystals. However, the possibilities of stress induced polymorphic transformation …
A review on micro-and nanoscratching/tribology at high temperatures: instrumentation and experimentation
SZ Chavoshi, S Xu - Journal of Materials Engineering and Performance, 2018 - Springer
High-temperature micro-/nanomechanics has attracted much interest over the last decade,
primarily because of the urgent need to understand the mechanical and tribological …
primarily because of the urgent need to understand the mechanical and tribological …
High Ratio of Hardness and Elastic Modulus (H/E) Studied by the Nanoindentation Technique of Acetaminophen with Corrugated Slip Planes
F Wei, W Zhang, C Zhang, Y Tian, S Wu… - Crystal Growth & …, 2022 - ACS Publications
Acetaminophen is a widely used analgesic and antipyretic drug. The mechanical properties
of drugs are vital for tableting and bioavailability. This paper studied the mechanical …
of drugs are vital for tableting and bioavailability. This paper studied the mechanical …
Molecular basis for the mechanical response of sulfa drug crystals
S SeethaLekshmi, MSRN Kiran… - … A European Journal, 2019 - Wiley Online Library
Comprehension of the nanomechanical response of crystalline materials requires the
understanding of the elastic and plastic deformation mechanisms in terms of the underlying …
understanding of the elastic and plastic deformation mechanisms in terms of the underlying …