MALAT1: A key regulator in lung cancer pathogenesis and therapeutic targeting
Lung cancer remains a formidable global health burden, necessitating a comprehensive
understanding of the underlying molecular mechanisms driving its progression. Recently …
understanding of the underlying molecular mechanisms driving its progression. Recently …
Comparing DESI-MSI and MALDI-MSI mediated spatial metabolomics and their applications in cancer studies
Metabolic heterogeneity of cancer contributes significantly to its poor treatment outcomes
and prognosis. As a result, studies continue to focus on identifying new biomarkers and …
and prognosis. As a result, studies continue to focus on identifying new biomarkers and …
Single-cell spatial metabolomics with cell-type specific protein profiling for tissue systems biology
Metabolic reprogramming in cancer and immune cells occurs to support their increasing
energy needs in biological tissues. Here we propose Single Cell Spatially resolved …
energy needs in biological tissues. Here we propose Single Cell Spatially resolved …
Mechanisms of resistance to chemotherapy in non-small cell lung cancer
HY Min, HY Lee - Archives of pharmacal research, 2021 - Springer
Non-small cell lung cancer (NSCLC), which represents 80–85% of lung cancer cases, is one
of the leading causes of human death worldwide. The majority of patients undergo an …
of the leading causes of human death worldwide. The majority of patients undergo an …
Current landscape of therapeutic resistance in lung cancer and promising strategies to overcome resistance
Simple Summary Despite an initial response to therapy, many lung cancer patients
inevitably develop resistance to therapy leading to decreased duration of response and …
inevitably develop resistance to therapy leading to decreased duration of response and …
Mitochondrial CPT1A: Insights into structure, function, and basis for drug development
K Liang - Frontiers in pharmacology, 2023 - frontiersin.org
Carnitine Palmitoyl-Transferase1A (CPT1A) is the rate-limiting enzyme in the fatty acid β-
oxidation, and its deficiency or abnormal regulation can result in diseases like metabolic …
oxidation, and its deficiency or abnormal regulation can result in diseases like metabolic …
Omics-based deep learning approaches for lung cancer decision-making and therapeutics development
Lung cancer has been the most common and the leading cause of cancer deaths globally.
Besides clinicopathological observations and traditional molecular tests, the advent of …
Besides clinicopathological observations and traditional molecular tests, the advent of …
[HTML][HTML] DNA methylation in lung cancer patients: Opening a" window of life" under precision medicine
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in
DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl …
DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl …
Reprogramming of lipid metabolism in lung cancer: An overview with focus on EGFR-Mutated non-small cell lung cancer
K Eltayeb, S La Monica, M Tiseo, R Alfieri, C Fumarola - Cells, 2022 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide. Most of lung cancer cases are
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …
Deep learning for lung cancer diagnosis, prognosis and prediction using histological and cytological images: a systematic review
Simple Summary Lung cancer is one of the most common and deadly malignancies
worldwide. Microscopic examination of histological and cytological lung specimens can be a …
worldwide. Microscopic examination of histological and cytological lung specimens can be a …