Pathophysiological mechanisms of renal fibrosis: a review of animal models and therapeutic strategies

A Nogueira, MJ Pires, PA Oliveira - In vivo, 2017 - iv.iiarjournals.org
Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work
correctly. It has a high prevalence and represents a serious hazard to human health and …

Acute kidney injury in diabetes mellitus

D Patschan, GA Müller - International journal of nephrology, 2016 - Wiley Online Library
Diabetes mellitus (DM) significantly increases the overall morbidity and mortality, particularly
by elevating the cardiovascular risk. The kidneys are severely affected as well, partly as a …

Factors associated with acute kidney injury in acute respiratory distress syndrome

A Panitchote, O Mehkri, A Hastings, T Hanane… - Annals of intensive …, 2019 - Springer
Background Acute kidney injury (AKI) is the most frequent extra-pulmonary organ failure in
acute respiratory distress syndrome (ARDS). The objective of this study was to assess the …

Hyperglycemia regulates hypoxia-inducible factor-1α protein stability and function

SB Catrina, K Okamoto, T Pereira, K Brismar… - Diabetes, 2004 - Am Diabetes Assoc
Hyperglycemia and hypoxia are suggested to play essential pathophysiological roles in the
complications of diabetes, which may result from a defective response of the tissues to low …

Сахарный диабет и артериальная гипертензия

ИИ Дедов, МВ Шестакова - 2006 - elibrary.ru
В книге представлены современные данные об этиологии и механизмах развития
артериальной гипертензии при сахарном диабете типа 1 и типа 2, о роли …

Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension

F Palm, J Cederberg, P Hansell, P Liss, PO Carlsson - Diabetologia, 2003 - Springer
Aims/hypothesis Augmented formation of reactive oxygen species (ROS) induced by
hyperglycaemia has been suggested to contribute to the development of diabetic …

Renal oxygenation and haemodynamics in acute kidney injury and chronic kidney disease

P Singh, SE Ricksten, G Bragadottir… - Clinical and …, 2013 - Wiley Online Library
Acute kidney injury (AKI) is a major burden on health systems and may arise from multiple
initiating insults, including ischaemia‐reperfusion injury, cardiovascular surgery …

[HTML][HTML] Difficulties in understanding human “acute tubular necrosis”: limited data and flawed animal models

S Rosen, NH Samuel - Kidney international, 2001 - Elsevier
Difficulties in understanding human “acute tubular necrosis”: Limited data and flawed animal
models. This review summarizes the current understanding of the renal biopsy in “acute …

Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs)

HE Mohamad, ME Askar, MM Hafez - Diabetology & metabolic syndrome, 2011 - Springer
Background Diabetes mellitus (DM) and hypertension (HTN) are accused of being
responsible for the development of the cardiac fibrosis due to severe cardiomyopathy …

Nephropathy in type 2 diabetes

E Ritz - Journal of internal medicine, 1999 - Wiley Online Library
End‐stage renal failure (ESRF) in diabetic patients, mostly type 2, has become the most
frequent cause of renal replacement therapy in western Europe. The majority of patients with …