[HTML][HTML] Unity among the diverse RNA-guided CRISPR-Cas interference mechanisms

C Ganguly, S Rostami, K Long, SD Aribam… - Journal of Biological …, 2024 - Elsevier
CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-
associated) systems are adaptive immune systems that protect bacteria and archaea from …

[HTML][HTML] Unlocking the secrets of ABEs: the molecular mechanism behind their specificity

X Chen, MJ McAndrew… - Biochemical Society …, 2023 - portlandpress.com
CRISPR–Cas, the bacterial immune systems, have transformed the field of genome editing
by providing efficient, easily programmable, and accessible tools for targeted genome …

Актуальные проблемы биоэкономики, роль постгеномных дисциплин

ЕС Титова, СС Шишкин - 2023 - elibrary.ru
В монографии обобщены современные представления о формировании и развитии
биоэкономики, что было обусловлено использованием крупных достижений наук о …

Substrate-independent activation pathways of the CRISPR-Cas9 HNH nuclease

J Wang, F Maschietto, T Qiu, PR Arantes, E Skeens… - Biophysical …, 2023 - cell.com
A hallmark of tightly regulated high-fidelity enzymes is that they become activated only after
encountering cognate substrates, often by an induced-fit mechanism rather than …

Advances in Nanoparticles as Non-Viral Vectors for Efficient Delivery of CRISPR/Cas9

M Kim, Y Hwang, S Lim, HK Jang, HO Kim - Pharmaceutics, 2024 - mdpi.com
The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system is a
gene-editing technology. Nanoparticle delivery systems have attracted attention because of …