Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-
stranded segmented RNA genome. They infect a wide range of animals, including humans …

Clinical isolates of influenza virus produce pleomorphic virus particles, including extremely
long filamentous virions. In contrast, strains of influenza that have adapted to laboratory …

Interactions between respiratory viruses during infection affect transmission dynamics and
clinical outcomes. To identify and characterize virus–virus interactions at the cellular level …

Viruses use virions to spread between hosts, and virion composition is therefore the primary
determinant of viral transmissibility and immunogenicity. However, the virions of many …

Influenza A virus causes millions of severe cases of disease during annual epidemics. The
most abundant protein in influenza virions is matrix protein 1 (M1), which mediates virus …

Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness
and host tropism. Binding to mucus decoy receptors and receptors on epithelial host cells is …

Human respiratory syncytial virus (RSV) causes severe respiratory illness in children and
the elderly. Here, using cryogenic electron microscopy and tomography combined with …

Respiratory syncytial virus (RSV), a member of the Paramyxoviridae family of
nonsegmented, negative-sense, single-stranded RNA genome viruses, is a leading cause of …

Attachment to and fusion with cell membranes are two major steps in the replication cycle of
many human viruses. We focus on these steps for three enveloped viruses, ie, HIV-1, IAVs …

The segmented genome of an influenza virus is encapsidated into ribonucleoprotein
complexes (RNPs). Unusually among RNA viruses, influenza viruses replicate in the …