The spectrum of neuromyelitis optica

DM Wingerchuk, VA Lennon, CF Lucchinetti… - The Lancet …, 2007 - thelancet.com
Neuromyelitis optica (also known as Devic's disease) is an idiopathic, severe, demyelinating
disease of the central nervous system that preferentially affects the optic nerve and spinal …

Neuromyelitis optica pathogenesis and aquaporin 4

DJ Graber, M Levy, D Kerr, WF Wade - Journal of neuroinflammation, 2008 - Springer
Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly
features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody …

A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis

VA Lennon, DM Wingerchuk, TJ Kryzer, SJ Pittock… - The Lancet, 2004 - thelancet.com
Background Neuromyelitis optica is an inflammatory demyelinating disease with generally
poor prognosis that selectively targets optic nerves and spinal cord. It is commonly …

Revised diagnostic criteria for neuromyelitis optica

DM Wingerchuk, VA Lennon, SJ Pittock… - Neurology, 2006 - AAN Enterprises
Background: The authors previously proposed diagnostic criteria for neuromyelitis optica
(NMO) that facilitate its distinction from prototypic multiple sclerosis (MS). However, some …

Differential diagnosis of suspected multiple sclerosis: a consensus approach

DH Miller, BG Weinshenker, M Filippi… - Multiple Sclerosis …, 2008 - journals.sagepub.com
Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of
diseases that could better explain the clinical and paraclinical findings. A systematic process …

Diagnosis and treatment of neuromyelitis optica

DM Wingerchuk - The neurologist, 2007 - journals.lww.com
Background: Neuromyelitis optica (NMO) is an uncommon CNS demyelinating syndrome
often mistaken for severe multiple sclerosis (MS). Several clinical, laboratory, and …

Natural history of the visual impairment of relapsing neuromyelitis optica

H Merle, S Olindo, M Bonnan, A Donnio, R Richer… - Ophthalmology, 2007 - Elsevier
PURPOSE: To describe the clinical features and natural history of the visual impairment of
relapsing neuromyelitis optica. DESIGN: Prospective observational case series …

Transverse myelitis

AT Borchers, ME Gershwin - Autoimmunity reviews, 2012 - Elsevier
Acute transverse myelitis (ATM) is an etiologically heterogeneous syndrome with acute or
subacute onset, in which inflammation of the spinal cord results in neurologic deficits …

Neuromyelitis optica with hypothalamic involvement

AY Poppe, Y Lapierre, D Melançon… - Multiple Sclerosis …, 2005 - journals.sagepub.com
We describe two cases of neuromyelitis optica (NMO) with clinical and radiographically
confirmed features of hypothalamic involvement, in the absence of other parenchymal brain …

Neuromyelitis optica: changing concepts

A Jacob, M Matiello, DM Wingerchuk… - Journal of …, 2007 - Elsevier
Neuromyelitis optica (NMO; Devic's disease) and the NMO spectrum disorders are idiopathic
inflammatory demyelinating disorders that affect the central nervous system and have a …