Drug delivery across the blood–brain barrier: recent advances in the use of nanocarriers
The blood–brain barrier (BBB) has a significant contribution to homeostasis and protection
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …
[HTML][HTML] Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results
JT Senders, IS Muskens, R Schnoor, AV Karhade… - Acta …, 2017 - Springer
Background Fluorescence-guided surgery (FGS) is a technique used to enhance
visualization of tumor margins in order to increase the extent of tumor resection in glioma …
visualization of tumor margins in order to increase the extent of tumor resection in glioma …
[HTML][HTML] Nanotheranostics: emerging strategies for early diagnosis and therapy of brain cancer
MK Viswanadh, RP Singh, P Agrawal… - …, 2018 - ncbi.nlm.nih.gov
Nanotheranostics have demonstrated the development of advanced platforms that can
diagnose brain cancer at early stages, initiate first-line therapy, monitor it, and if needed …
diagnose brain cancer at early stages, initiate first-line therapy, monitor it, and if needed …
[HTML][HTML] Hydrogel-based drug delivery nanosystems for the treatment of brain tumors
Chemotherapy is commonly associated with limited effectiveness and unwanted side effects
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …
Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies
Objective Fluorescence guidance has a demonstrated potential in maximizing the extent of
high-grade glioma resection. Different fluorophores (fluorescent biomarkers), including 5 …
high-grade glioma resection. Different fluorophores (fluorescent biomarkers), including 5 …
[HTML][HTML] Intraoperative fluorescence imaging for personalized brain tumor resection: current state and future directions
Introduction Fluorescence-guided surgery is one of the rapidly emerging methods of surgical
“theranostics.” In this review, we summarize current fluorescence techniques used in …
“theranostics.” In this review, we summarize current fluorescence techniques used in …
[HTML][HTML] In vivo quantitative imaging of tumor pH by nanosonophore assisted multispectral photoacoustic imaging
Abstract Changes of physiological pH are correlated with several pathologies, therefore the
development of more effective medical pH imaging methods is of paramount importance …
development of more effective medical pH imaging methods is of paramount importance …
Cell surface nucleolin as a target for anti-cancer therapies
M Koutsioumpa, E Papadimitriou - Recent patents on anti …, 2014 - ingentaconnect.com
A large number of mostly recent reports show enhanced expression of the multi-functional
protein nucleolin (NCL) on the surface of activated lymphocytes, angiogenic endothelial and …
protein nucleolin (NCL) on the surface of activated lymphocytes, angiogenic endothelial and …
Review of neurosurgical fluorescence imaging methodologies
BW Pogue, SL Gibbs-Strauss… - IEEE Journal of …, 2010 - ieeexplore.ieee.org
Fluorescence imaging in neurosurgery has a long historical development, with various
biomarkers and biochemical agents being used, and numerous technological approaches …
biomarkers and biochemical agents being used, and numerous technological approaches …
Nanoparticles with targeting, triggered release, and imaging functionality for cancer applications
The tendency for nanoparticles to accumulate in tumor regions as a result of the enhanced
permeability and retention effect has proven to be an advantageous feature for delivery of …
permeability and retention effect has proven to be an advantageous feature for delivery of …