Advances of hyphenated technique in impurity profiling of active pharmaceutical ingredients and pharmaceutical products

N Khandale, RR Rajge, SK Singh… - Separation Science …, 2023 - Wiley Online Library
Impurities found in active pharmaceutical ingredients (APIs) and pharmaceutical products
are of ever‐increasing interest. According to several regulatory agencies, purity and impurity …

Separation and quantitation of valacyclovir enantiomers using stability‐indicating chiral liquid chromatography method with a chiral stationary phase of amylose tris‐(3 …

N Vadagam, SB Haridasyam… - Separation …, 2023 - Wiley Online Library
The present research developed and validated a new stability‐indicating technique for the
stereo‐selectively enantiomers of the antiviral nucleoside analog Valacyclovir hydrochloride …

Separation and simultaneous estimation of enantiomers and Diastereomers of muscarinic receptor antagonist Solifenacin using stability‐indicating Normal‐phase …

N Vadagam, SB Haridasyam, M Venkatanarayana… - Chirality, 2024 - Wiley Online Library
The R, S‐enantiomer impurity and diastereomer impurities (S, S‐isomer and R, R‐isomer) of
the solifenacin (S, R‐enantiomer) were effectively separated and quantified simultaneously …

A voltammetric sensor based on aluminophosphate zeolite and a composite of betulinic acid with a chitosan polyelectrolyte complex for the identification and …

RA Zilberg, VN Maistrenko, YB Teres, IV Vakulin… - Journal of Analytical …, 2023 - Springer
A voltammetric sensor was developed based on a glassy carbon electrode with
aluminophosphate zeolite finely dispersed on its surface, modified with a polyelectrolyte …

Вольтамперометрический сенсор на основе алюмофосфатного цеолита и композита бетулиновой кислоты с полиэлектролитным комплексом хитозана для …

РА Зильберг, ВН Майстренко, ЮБ Терес… - Журнал …, 2023 - elibrary.ru
Разработан вольтамперометрический сенсор на основе стеклоуглеродного электрода
с осажденным на его поверхности мелкодисперсным алюмофосфатным цеолитом …

Review of Applications of β-Cyclodextrin as a Chiral Selector for Effective Enantioseparation

E Napiórkowska, Ł Szeleszczuk - International Journal of Molecular …, 2024 - mdpi.com
The significance and necessity of separating enantiomers in food, pharmaceuticals,
pesticides, and other samples remains constant and unrelenting. The successful chiral …

Click-imprinted furan-modified poly (acrylonitrile-co-divinylbenzene for S-naproxen recognition

HY Alharbi, RB Alnoman, MS Aljohani, M Monier… - Reactive and Functional …, 2024 - Elsevier
Naproxen (NX) drug exists in two R-and S-enantiomers, requiring enantioseparation for
effective pharmacological effects. Herein, a new S-NX enantioselective poly (acrylonitrile-co …

Fluorescent nanoprobe for detection of naproxen based on doped carbon dots prepared in choline chloride-thiourea deep eutectic solvent

R Tabaraki, F Nazari - Journal of the Iranian Chemical Society, 2023 - Springer
Choline chloride-thiourea deep eutectic solvent (DES) was prepared and used to microwave-
assisted synthesis of nitrogen, sulfur, and chloride doped carbon dots (N, S, Cl-CDs). In this …

Molecularly imprinted hydrazidine‐derived poly (acrylonitrile‐co‐divinylbenzene for enantio‐recognition of S‐fenoprofen

AA Alhawaiti, FM Almutairi… - Journal of Applied …, 2024 - Wiley Online Library
The drug fenoprofen (FN) is available in two forms, R‐and S‐enantiomers, which need to be
separated for optimal therapeutic use. A novel poly (acrylonitrile‐co‐divinylbenzene)(PNB) …

Determination of naproxen in mixtures of water and an organic solvent based on chemiluminescence of reaction mixtures containing europium ions

M Kaczmarek, K Staninski - Journal of Photochemistry and Photobiology A …, 2024 - Elsevier
A simple and sensitive method, based on chemiluminescence of a reaction system
containing europium (III) ions, for determination of naproxen in mixed solvents of water and …